Literature DB >> 26030484

Imposing genetic diversity.

Robert Sparrow1.   

Abstract

The idea that a world in which everyone was born "perfect" would be a world in which something valuable was missing often comes up in debates about the ethics of technologies of prenatal testing and preimplantation genetic diagnosis (PGD). This thought plays an important role in the "disability critique" of prenatal testing. However, the idea that human genetic variation is an important good with significant benefits for society at large is also embraced by a wide range of figures writing in the bioethics literature, including some who are notoriously hostile to the idea that we should not select against disability. By developing a number of thought experiments wherein we are to contemplate increasing genetic diversity from a lower baseline in order to secure this value, I argue that this powerful intuition is more problematic than is generally recognized, especially where the price of diversity is the well-being of particular individuals.

Entities:  

Keywords:  PGD; disability; diversity; ethics; human enhancement; prenatal testing

Mesh:

Year:  2015        PMID: 26030484     DOI: 10.1080/15265161.2015.1028658

Source DB:  PubMed          Journal:  Am J Bioeth        ISSN: 1526-5161            Impact factor:   11.229


  4 in total

1.  Reproductive genetic testing and human genetic variation in the era of genomic medicine.

Authors:  Chelsea Lowther; Gregory Costain; Anne S Bassett
Journal:  Am J Bioeth       Date:  2015       Impact factor: 11.229

Review 2.  Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing.

Authors:  Ruth Horn; Michael Parker
Journal:  Prenat Diagn       Date:  2017-08-07       Impact factor: 3.050

3.  Withholding or withdrawing life-sustaining treatment in extremely low gestational age neonates.

Authors:  April R Dworetz; Girija Natarajan; John Langer; Kathy Kinlaw; Jennifer R James; Margarita Bidegain; Abhik Das; Brenda Poindexter; Edward F Bell; C M Cotten; Haresh Kirpalani; Seetha Shankaran; Barbara J Stoll
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2020-10-20       Impact factor: 5.747

Review 4.  Principles of Genetic Counseling in the Era of Next-Generation Sequencing.

Authors:  Mina Yang; Jong Won Kim
Journal:  Ann Lab Med       Date:  2018-07       Impact factor: 3.464

  4 in total

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