Literature DB >> 26029654

Glow in the dark.

Loucas Christodoulou1, Kit Wu1.   

Abstract

OBJECTIVE: To highlight the importance of radiation safety and handling of radioactive secretions following 131I-meta iodobenzylguanidine (131I-mIBG) use in the treatment of neuroblastoma.
METHODS: We report a 4-year-old girl with stage 4 neuroblastoma, on whom's single-photon emission computer tomography (SPECT) scan we demonstrate four extra-corporal areas of radioactivity confirming radiation uptake in the four corners of her 'comfort blanket' that had been used to cover her during the scan. It transpired that she had been sucking on the four corners of this blanket.
RESULTS: The patient's secretions remain radioactive for some time following scintigraphy, as evidence of radioactivity in the patient's comfort blanket.
CONCLUSIONS: Radioactive uptake of 131I-mIBG in the salivary glands of patients has previously been reported. This illustrative case emphasizes that patient's secretions remain radioactive following treatment and highlights the importance of careful handling of radioactive secretions.

Entities:  

Keywords:  131I-meta iodobenzylguanidine (131I-mIBG); SPECT scan; neuroblastoma; radiation safety; salivary uptake

Year:  2015        PMID: 26029654      PMCID: PMC4426114          DOI: 10.3978/j.issn.2223-4292.2014.11.29

Source DB:  PubMed          Journal:  Quant Imaging Med Surg        ISSN: 2223-4306


  2 in total

Review 1.  Optimization of molecular radiotherapy with [131I]-meta Iodobenzylguanidine for high-risk neuroblastoma.

Authors:  M N Gaze; J E Gains; C Walker; J B Bomanji
Journal:  Q J Nucl Med Mol Imaging       Date:  2013-03       Impact factor: 2.346

2.  Salivary gland accumulation of meta-[131I]iodobenzylguanidine.

Authors:  M Nakajo; B Shapiro; J C Sisson; D P Swanson; W H Beierwaltes
Journal:  J Nucl Med       Date:  1984-01       Impact factor: 10.057

  2 in total
  1 in total

1.  Feasibility of Administering High-Dose (131) I-MIBG Therapy to Children with High-Risk Neuroblastoma Without Lead-Lined Rooms.

Authors:  Bae P Chu; Christopher Horan; Ellen Basu; Lawrence Dauer; Matthew Williamson; Jorge A Carrasquillo; Neeta Pandit-Taskar; Shakeel Modak
Journal:  Pediatr Blood Cancer       Date:  2016-01-15       Impact factor: 3.167

  1 in total

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