Literature DB >> 26029335

Dermabrasion: a novel treatment for diffuse silicone granuloma.

Mina Zarei1, Daniel Levy1, Francisco A Kerdel1, Christopher J Salgado2, Paolo Romanelli1.   

Abstract

OBJECTIVE: Formation of a foreign body granuloma is one of the serious complications of silicone injection, which can be difficult to treat. In this paper, the authors report their successful experience with dermabrasion as an innovative treatment in a patient who presented with diffuse silicone granuloma. CASE REPORT: The patient was a 51-year-old woman, with areas of induration and hyperpigmentation on both her legs with intermittent fevers and generalized malaise. The patient had a history of numerous bilateral hip injections of liquid silicone five years ago for cosmetic purposes. A skin biopsy showed a foreign-body granuloma consistent with a paraffinoma with "Swiss cheese" appearance. After unsuccessful medical therapy and liposuction, an extensive bilateral dermabrasion was performed on both legs. Postoperatively, her wounds exuded a collection of thick, yellow viscous fluid under the transparent semi-occlusive dressings, which showed a markedly elevated level of silicone after analysis. She experienced no complication related to dermabrasion.
CONCLUSION: The findings of this case demonstrate that dermabrasion may be an effective treatment option for diffuse silicone granuloma, particularly when the material resides superficially in the dermis.

Entities:  

Year:  2015        PMID: 26029335      PMCID: PMC4445896     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  4 in total

Review 1.  Injectable silicone: cause of facial nodules, cellulitis, ulceration, and migration.

Authors:  M J Rapaport; C Vinnik; H Zarem
Journal:  Aesthetic Plast Surg       Date:  1996 May-Jun       Impact factor: 2.326

2.  Silicone granuloma of the face treated with minocycline.

Authors:  Meral J Arin; Jens Bäte; Thomas Krieg; Nicolas Hunzelmann
Journal:  J Am Acad Dermatol       Date:  2005-02       Impact factor: 11.527

3.  Injectable fluid silicone therapy. Human morbidity and mortality.

Authors:  R Ellenbogen; L Rubin
Journal:  JAMA       Date:  1975-10-20       Impact factor: 56.272

4.  Lip silicone granulomatous foreign body reaction treated with aldara (imiquimod 5%).

Authors:  Leslie S Baumann; Monica L Halem
Journal:  Dermatol Surg       Date:  2003-04       Impact factor: 3.398

  4 in total

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