L C Hartog1, M Cizmar-Sweelssen2, A Knipscheer2, K H Groenier3, N Kleefstra4, H J G Bilo5, K J J van Hateren6. 1. Diabetes Centre, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands. Electronic address: l.c.hartog@isala.nl. 2. TriviumMeulenbeltZorg, PC Borstlaan 10, 7555 SH Hengelo, The Netherlands. 3. Diabetes Centre, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands; University Medical Center Groningen and University of Groningen, Department of General Practice, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. 4. Diabetes Centre, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands; University Medical Center Groningen and University of Groningen, Department of Internal Medicine, Hanzeplein 1, 9700 RB Groningen, The Netherlands. 5. Diabetes Centre, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands; University Medical Center Groningen and University of Groningen, Department of Internal Medicine, Hanzeplein 1, 9700 RB Groningen, The Netherlands; Isala, Department of Internal Medicine, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands. 6. Diabetes Centre, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands.
Abstract
PURPOSE OF THE STUDY: Our objectives were to identify the prevalence of orthostatic hypotension (OH) in frail, elderly nursing home residents, and assess its possible association with falling and chances of successful rehabilitation. MATERIALS AND METHODS: A prospective observational cohort study. A total of 290 patients participated in this study, of which 128 were admitted to the rehabilitation department. OH was defined as a drop in systolic blood pressure of >20mmHg and diastolic blood pressure of >10mmHg after postural change within 3min. The analyses regarding falling and successful rehabilitation were only performed in the rehabilitation group. Multivariate binary logistic regression analyses were used to describe risk factors related with falling. Cox proportional hazard modeling was used to investigate the relation between OH and the time to successful rehabilitation. RESULTS: The prevalence of OH in the studied nursing home population was 36.6% (95% CI (confidence interval): 31.1-42.1%). The prevalence varied from 28.6% (95% CI: 16.8-40.4%) in somatic patients, 36.7% (95% CI: 28.4-45.1%) in rehabilitation patients, to 40.6% (95% CI: 31.3-50.0%) in psychogeriatric patients. The association between orthostatic hypotension and previous falling was not significant; Odds ratio 0.66 (95% CI: 0.30-1.48). The Hazard ratio of the relationship between OH and successful rehabilitation was 2.88 (95% CI:1.77-4.69). CONCLUSIONS: OH is highly prevalent in nursing home residents. Surprisingly, patients with OH were found to have a higher chance of successful rehabilitation compared to patients without OH. If confirmed in other studies, these results may change our view of the implications of OH.
PURPOSE OF THE STUDY: Our objectives were to identify the prevalence of orthostatic hypotension (OH) in frail, elderly nursing home residents, and assess its possible association with falling and chances of successful rehabilitation. MATERIALS AND METHODS: A prospective observational cohort study. A total of 290 patients participated in this study, of which 128 were admitted to the rehabilitation department. OH was defined as a drop in systolic blood pressure of >20mmHg and diastolic blood pressure of >10mmHg after postural change within 3min. The analyses regarding falling and successful rehabilitation were only performed in the rehabilitation group. Multivariate binary logistic regression analyses were used to describe risk factors related with falling. Cox proportional hazard modeling was used to investigate the relation between OH and the time to successful rehabilitation. RESULTS: The prevalence of OH in the studied nursing home population was 36.6% (95% CI (confidence interval): 31.1-42.1%). The prevalence varied from 28.6% (95% CI: 16.8-40.4%) in somatic patients, 36.7% (95% CI: 28.4-45.1%) in rehabilitation patients, to 40.6% (95% CI: 31.3-50.0%) in psychogeriatric patients. The association between orthostatic hypotension and previous falling was not significant; Odds ratio 0.66 (95% CI: 0.30-1.48). The Hazard ratio of the relationship between OH and successful rehabilitation was 2.88 (95% CI:1.77-4.69). CONCLUSIONS: OH is highly prevalent in nursing home residents. Surprisingly, patients with OH were found to have a higher chance of successful rehabilitation compared to patients without OH. If confirmed in other studies, these results may change our view of the implications of OH.
Authors: Anna C Breeuwsma; Laura C Hartog; Adriaan M Kamper; Klaas H Groenier; Henk Jg Bilo; Nanne Kleefstra; Kornelis Jj Van Hateren Journal: Hypertens Res Date: 2017-03-16 Impact factor: 3.872
Authors: Anna C Breeuwsma; Laura C Hartog; Adriaan M Kamper; Klaas H Groenier; Henk J G Bilo; Nanne Kleefstra; Kornelis J J Van Hateren Journal: J Hum Hypertens Date: 2018-08-14 Impact factor: 3.012