Literature DB >> 26025062

A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.

Inho Yang1, Hyukjae Choi2, Sang-Jip Nam3, Heonjoong Kang4,5.   

Abstract

An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 μg ml(-1), respectively.

Entities:  

Keywords:  Antibacterial; Ircinia; Marine natural product; Secosterol; Sponge

Mesh:

Substances:

Year:  2015        PMID: 26025062     DOI: 10.1007/s12272-015-0620-9

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN: 0253-6269            Impact factor:   4.946


  2 in total

Review 1.  Marine Pharmacology in 2014-2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors:  Alejandro M S Mayer; Aimee J Guerrero; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Fumiaki Nakamura; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2019-12-19       Impact factor: 5.118

2.  New 9α-Hydroxy-5α,6α-epoxyhydroxysterols from the Vietnamese Marine Sponge Ircinia echinata.

Authors:  Thi Thanh Van Trinh; Bich Ngan Truong; Arlette Longeon; Thi Mai Huong Doan; Alexandre Deville; Van Minh Chau; Van Cuong Pham; Marie-Lise Bourguet-Kondracki
Journal:  Mar Drugs       Date:  2018-11-01       Impact factor: 5.118

  2 in total

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