Literature DB >> 26023665

Pulp Revascularization- It's your Future Whether you Know it or Not?

Pooja Gupta Dudeja1, Shibani Grover2, Dhirendra Srivastava3, Krishan Kumar Dudeja4, Vivek Sharma5.   

Abstract

Pulpal regeneration after tooth injury is not easy to accomplish. In teeth with immature apices and exposed vital pulp tissue, partial or complete pulpotomy is indicated to preserve pulpal function and allow continued root development. In many cases, injury causes loss of pulp vitality and arrested root development leading to a tooth with poor crown root ratio, a root with very thin walls, an open blunderbuss apex and development of apical pathosis. The ideal treatment in such cases would be to obtain further root development and thickening of dentinal walls by stimulating the regeneration of a functional pulp dentin complex. This outcome has been observed after reimplantation in avulsed immature permanent teeth but has been thought impossible in a necrotic infected tooth. This case series evaluates the efficacy of revascularization procedure in immature, non vital permanent teeth. Pulp regeneration was attempted in four patients at Department of Conservative Dentistry, ESIC Dental College, New Delhi using blood clotting approach. The cases were treated and followed up regularly at regular intervals ranging from 6 months to 3 years to assess the treatment response clinically and radiographically. The patients remained clinically asymptomatic with three out of four patients even responding positively to pulp responsiveness tests. Radiographic examination also revealed increased root formation and thickening of dentinal walls. It was concluded that the triad of a disinfected canal, a matrix (blood clot) in to which new tissue could grow and an effective coronal seal produced the desirable environment for successful revascularization.

Entities:  

Keywords:  Blood clotting; Immature/open apex; Non-vital teeth; Pulp revascularization

Year:  2015        PMID: 26023665      PMCID: PMC4437181          DOI: 10.7860/JCDR/2015/10149.5768

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  23 in total

1.  Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol?

Authors:  Francisco Banchs; Martin Trope
Journal:  J Endod       Date:  2004-04       Impact factor: 4.171

Review 2.  Mineral trioxide aggregate: a comprehensive literature review--part II: leakage and biocompatibility investigations.

Authors:  Mahmoud Torabinejad; Masoud Parirokh
Journal:  J Endod       Date:  2010-02       Impact factor: 4.171

Review 3.  Regeneration potential of the young permanent tooth: what does the future hold?

Authors:  Kenneth M Hargreaves; Todd Giesler; Michael Henry; Yan Wang
Journal:  J Endod       Date:  2008-07       Impact factor: 4.171

Review 4.  The hidden treasure in apical papilla: the potential role in pulp/dentin regeneration and bioroot engineering.

Authors:  George T-J Huang; Wataru Sonoyama; Yi Liu; He Liu; Songlin Wang; Songtao Shi
Journal:  J Endod       Date:  2008-06       Impact factor: 4.171

5.  Longitudinal sealing ability of mineral trioxide aggregate as a root-end filling material.

Authors:  C F Bates; D L Carnes; C E del Rio
Journal:  J Endod       Date:  1996-11       Impact factor: 4.171

Review 6.  Clinical considerations for regenerative endodontic procedures.

Authors:  Todd M Geisler
Journal:  Dent Clin North Am       Date:  2012-07

7.  A new population of human adult dental pulp stem cells: a useful source of living autologous fibrous bone tissue (LAB).

Authors:  Gregorio Laino; Riccardo d'Aquino; Antonio Graziano; Vladimiro Lanza; Francesco Carinci; Fabio Naro; Giuseppe Pirozzi; Gianpaolo Papaccio
Journal:  J Bone Miner Res       Date:  2005-03-28       Impact factor: 6.741

8.  Investigation of multipotent postnatal stem cells from human periodontal ligament.

Authors:  Byoung-Moo Seo; Masako Miura; Stan Gronthos; Peter Mark Bartold; Sara Batouli; Jaime Brahim; Marian Young; Pamela Gehron Robey; Cun-Yu Wang; Songtao Shi
Journal:  Lancet       Date:  2004 Jul 10-16       Impact factor: 79.321

9.  Regenerative treatment of an immature, traumatized tooth with apical periodontitis: report of a case.

Authors:  Elisabetta Cotti; Manuela Mereu; Daniela Lusso
Journal:  J Endod       Date:  2008-05       Impact factor: 4.171

Review 10.  Regenerative endodontics: a review of current status and a call for action.

Authors:  Peter E Murray; Franklin Garcia-Godoy; Kenneth M Hargreaves
Journal:  J Endod       Date:  2007-02-20       Impact factor: 4.171

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  4 in total

1.  Cytotoxicity and osteogenic potential of silicate calcium cements as potential protective materials for pulpal revascularization.

Authors:  Eduardo A Bortoluzzi; Li-Na Niu; Chithra D Palani; Ahmed R El-Awady; Barry D Hammond; Dan-Dan Pei; Fu-Cong Tian; Christopher W Cutler; David H Pashley; Franklin R Tay
Journal:  Dent Mater       Date:  2015-10-19       Impact factor: 5.304

2.  Comparative evaluation of Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin (PRF) scaffolds in regenerative endodontic treatment of immature necrotic permanent maxillary central incisors: A double blinded randomized controlled trial.

Authors:  Hazim Mohamed Rizk; Mohamed Sherif Mohamed Salah Al-Deen; Asmaa Aly Emam
Journal:  Saudi Dent J       Date:  2019-09-21

3.  Modified Revascularization in Human Teeth Using an Intracanal Formation of Treated Dentin Matrix: A Report of Two Cases.

Authors:  Payman Mehrvarzfar; Paul V Abbott; Hengameh Akhavan; Sohrab Tour Savadkouhi
Journal:  J Int Soc Prev Community Dent       Date:  2017-07-31

4.  What is the best long-term treatment modality for immature permanent teeth with pulp necrosis and apical periodontitis?

Authors:  A Wikström; M Brundin; M F Lopes; M El Sayed; G Tsilingaridis
Journal:  Eur Arch Paediatr Dent       Date:  2021-01-08
  4 in total

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