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Literature DB >> 26022918

Clarifying the role of condensin in shaping chromosomes.

Abstract

A major controversy in the field of chromosome research has been whether condensin is required for achieving the highly compacted state of chromatin fibres in mitosis and meiosis. Through genetic experiments in mouse oocytes, condensin is now found to be indispensable for meiotic chromosome assembly by mediating chromosome compaction and disentanglement of sister chromatids and by conferring rigidity to chromosomes.

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Year: 2015 PMID： 26022918 DOI： 10.1038/ncb3183

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

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References

16 in total

1. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.

Authors: Takao Ono; Ana Losada; Michiko Hirano; Michael P Myers; Andrew F Neuwald; Tatsuya Hirano
Journal: Cell Date: 2003-10-03 Impact factor: 41.582

2. Real-time detection of single-molecule DNA compaction by condensin I.

Authors: Terence R Strick; Tatsuhiko Kawaguchi; Tatsuya Hirano
Journal: Curr Biol Date: 2004-05-25 Impact factor: 10.834

3. Drosophila CAP-D2 is required for condensin complex stability and resolution of sister chromatids.

Authors: Ellada Savvidou; Neville Cobbe; Søren Steffensen; Sue Cotterill; Margarete M S Heck
Journal: J Cell Sci Date: 2005-06-01 Impact factor: 5.285

4. Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.

Authors: Daniel Gerlich; Toru Hirota; Birgit Koch; Jan-Michael Peters; Jan Ellenberg
Journal: Curr Biol Date: 2006-02-21 Impact factor: 10.834

Review 5. Deciphering condensin action during chromosome segregation.

Authors: Sara Cuylen; Christian H Haering
Journal: Trends Cell Biol Date: 2011-07-15 Impact factor: 20.808

Review 6. Condensin, chromatin crossbarring and chromosome condensation.

Authors: Rahul Thadani; Frank Uhlmann; Sebastian Heeger
Journal: Curr Biol Date: 2012-12-04 Impact factor: 10.834

7. The condensin I subunit Barren/CAP-H is essential for the structural integrity of centromeric heterochromatin during mitosis.

Authors: Raquel A Oliveira; Paula A Coelho; Claudio E Sunkel
Journal: Mol Cell Biol Date: 2005-10 Impact factor: 4.272