| Literature DB >> 26018894 |
Abstract
A new large-scale study reports the whole-genome sequences of nearly 2,000 Salmonella enterica serovar Typhi (S. Typhi) strains collected from 63 countries. A recent and dominant multidrug-resistant (MDR) lineage originating from South Asia, which is supplanting a bulk of ancestral drug-sensitive strains, is identified; the success of this lineage is likely driven by plasmid acquisitions and the chromosomal integration of resistance-conferring genes.Entities:
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Year: 2015 PMID： 26018894 DOI： 10.1038/ng.3318
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330