Literature DB >> 26018593

Freezing of gait: a practical approach to management.

Jorik Nonnekes1, Anke H Snijders2, John G Nutt3, Günter Deuschl4, Nir Giladi5, Bastiaan R Bloem6.   

Abstract

Freezing of gait is a common and disabling symptom in patients with parkinsonism, characterised by sudden and brief episodes of inability to produce effective forward stepping. These episodes typically occur during gait initiation or turning. Treatment is important because freezing of gait is a major risk factor for falls in parkinsonism, and a source of disability to patients. Various treatment approaches exist, including pharmacological and surgical options, as well as physiotherapy and occupational therapy, but evidence is inconclusive for many approaches, and clear treatment protocols are not available. To address this gap, we review medical and non-medical treatment strategies for freezing of gait and present a practical algorithm for the management of this disorder, based on a combination of evidence, when available, and clinical experience of the authors. Further research is needed to formally establish the merits of our proposed treatment protocol.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID: 26018593     DOI: 10.1016/S1474-4422(15)00041-1

Source DB:  PubMed          Journal:  Lancet Neurol        ISSN: 1474-4422            Impact factor:   44.182


  95 in total

1.  Biomechanical Evaluation of Virtual Reality-based Turning on a Self-Paced Linear Treadmill.

Authors:  Keonyoung Oh; Christopher J Stanley; Diane L Damiano; Jonghyun Kim; Jungwon Yoon; Hyung-Soon Park
Journal:  Gait Posture       Date:  2018-07-24       Impact factor: 2.840

Review 2.  Clinical and methodological challenges for assessing freezing of gait: Future perspectives.

Authors:  Martina Mancini; Bastiaan R Bloem; Fay B Horak; Simon J G Lewis; Alice Nieuwboer; Jorik Nonnekes
Journal:  Mov Disord       Date:  2019-05-02       Impact factor: 10.338

3.  Staircase climbing is not solely a visual compensation strategy to alleviate freezing of gait in Parkinson's disease.

Authors:  M Gilat; J M Hall; K A Ehgoetz Martens; J M Shine; C C Walton; H G MacDougall; S T Moore; Simon J G Lewis
Journal:  J Neurol       Date:  2016-11-29       Impact factor: 4.849

4.  Brain plasticity in Parkinson's disease with freezing of gait induced by action observation training.

Authors:  Federica Agosta; Roberto Gatti; Elisabetta Sarasso; Maria Antonietta Volonté; Elisa Canu; Alessandro Meani; Lidia Sarro; Massimiliano Copetti; Erik Cattrysse; Eric Kerckhofs; Giancarlo Comi; Andrea Falini; Massimo Filippi
Journal:  J Neurol       Date:  2016-10-24       Impact factor: 4.849

5.  Identifying the neural correlates of doorway freezing in Parkinson's disease.

Authors:  Elie Matar; James M Shine; Moran Gilat; Kaylena A Ehgoetz Martens; Philip B Ward; Michael J Frank; Ahmed A Moustafa; Sharon L Naismith; Simon J G Lewis
Journal:  Hum Brain Mapp       Date:  2019-01-13       Impact factor: 5.038

6.  The role of the prefrontal cortex in freezing of gait in Parkinson's disease: insights from a deep repetitive transcranial magnetic stimulation exploratory study.

Authors:  Moria Dagan; Talia Herman; Anat Mirelman; Nir Giladi; Jeffrey M Hausdorff
Journal:  Exp Brain Res       Date:  2017-05-16       Impact factor: 1.972

7.  A Personalized Approach to Parkinson's Disease Patients Based on Founder Mutation Analysis.

Authors:  Nir Giladi; Anat Mirelman; Avner Thaler; Avi Orr-Urtreger
Journal:  Front Neurol       Date:  2016-05-10       Impact factor: 4.003

8.  A painted staircase illusion to alleviate freezing of gait in Parkinson's disease.

Authors:  Sabine Janssen; Mileha Soneji; Jorik Nonnekes; Bastiaan R Bloem
Journal:  J Neurol       Date:  2016-06-13       Impact factor: 4.849

9.  Brain structural and functional connectivity in Parkinson's disease with freezing of gait.

Authors:  Elisa Canu; Federica Agosta; Elisabetta Sarasso; Maria Antonietta Volontè; Silvia Basaia; Tanja Stojkovic; Elka Stefanova; Giancarlo Comi; Andrea Falini; Vladimir S Kostic; Roberto Gatti; Massimo Filippi
Journal:  Hum Brain Mapp       Date:  2015-09-11       Impact factor: 5.038

Review 10.  Neurological disorders of gait, balance and posture: a sign-based approach.

Authors:  Jorik Nonnekes; Rianne J M Goselink; Evžen Růžička; Alfonso Fasano; John G Nutt; Bastiaan R Bloem
Journal:  Nat Rev Neurol       Date:  2018-01-29       Impact factor: 42.937

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