Literature DB >> 26016928

Gecko gaskets for self-sealing and high-strength reversible bonding of microfluidics.

A Wasay1, D Sameoto.   

Abstract

We report in this work a novel reversible bonding technique for elastomeric microfluidic devices by integrating gecko-inspired dry adhesives with microfluidic channels which greatly enhances the bonding strength of reversibly sealed channels. The concept is applicable to nearly any elastomer and can be used to bond against any smooth surface which allows for van der Waals interactions. It does not require any solvents or glues or sources for plasma activation or thermal-compressive loading to aid the bonding process and is achievable at zero extra cost. We also demonstrate a quick fabrication technique involving soft master thermo-compressive molding of these microfluidic devices with thermoplastic elastomers. The resultant devices can be used for both pressure driven and non-pressure driven flows. We report the maximum contained pressure of these devices manufactured from two grades of styrene ethylene butylene styrene (SEBS) by conducting a burst pressure test with various substrates.

Entities:  

Year:  2015        PMID: 26016928     DOI: 10.1039/c5lc00342c

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  5 in total

1.  Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology.

Authors:  David E Watson; Rosemarie Hunziker; John P Wikswo
Journal:  Exp Biol Med (Maywood)       Date:  2017-10

2.  Polycaprolactone-enabled sealing and carbon composite electrode integration into electrochemical microfluidics.

Authors:  Kevin J Klunder; Kaylee M Clark; Cynthia McCord; Kathleen E Berg; Shelley D Minteer; Charles S Henry
Journal:  Lab Chip       Date:  2019-06-28       Impact factor: 6.799

3.  Plasma free reversible and irreversible microfluidic bonding.

Authors:  M Chu; T T Nguyen; E K Lee; J L Morival; M Khine
Journal:  Lab Chip       Date:  2017-01-17       Impact factor: 7.517

4.  Multiscale Soft Surface Instabilities for Adhesion Enhancement.

Authors:  Vaisakh Vilavinalthundil Mohanan; Ho Yi Lydia Mak; Nishan Gurung; Qin Xu
Journal:  Materials (Basel)       Date:  2022-01-23       Impact factor: 3.623

5.  Self-regenerating and hybrid irreversible/reversible PDMS microfluidic devices.

Authors:  Letícia S Shiroma; Maria H O Piazzetta; Gerson F Duarte-Junior; Wendell K T Coltro; Emanuel Carrilho; Angelo L Gobbi; Renato S Lima
Journal:  Sci Rep       Date:  2016-05-16       Impact factor: 4.379

  5 in total

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