Literature DB >> 26015069

Biological and medicinal significance of benzofuran.

Reshma J Nevagi1, Santosh N Dighe2, Satish N Dighe3.   

Abstract

This article emphasizes on the importance of benzofuran as a biologically relevant heterocycle. It covers most of the physiologically as well as medicinally important compounds containing benzofuran rings. This article also covers clinically approved drugs containing benzofuran scaffold.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Benzofuran; Biological significance; Enzyme; Inhibition

Mesh:

Substances:

Year:  2014        PMID: 26015069     DOI: 10.1016/j.ejmech.2014.10.085

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  34 in total

1.  Development of 3-methyl/3-(morpholinomethyl)benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells.

Authors:  Mohammad M Al-Sanea; Ghada H Al-Ansary; Zainab M Elsayed; Raed M Maklad; Eslam B Elkaeed; Mohamed A Abdelgawad; Syed Nasir Abbas Bukhari; Marwa M Abdel-Aziz; Howayda Suliman; Wagdy M Eldehna
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

2.  Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes.

Authors:  Michael M Yamano; Rachel R Knapp; Aurapat Ngamnithiporn; Melissa Ramirez; Kendall N Houk; Brian M Stoltz; Neil K Garg
Journal:  Angew Chem Int Ed Engl       Date:  2019-03-20       Impact factor: 15.336

3.  Expanding the Strained Alkyne Toolbox: Generation and Utility of Oxygen-Containing Strained Alkynes.

Authors:  Tejas K Shah; Jose M Medina; Neil K Garg
Journal:  J Am Chem Soc       Date:  2016-03-29       Impact factor: 15.419

4.  Biocatalytic Strategy for Highly Diastereo- and Enantioselective Synthesis of 2,3-Dihydrobenzofuran-Based Tricyclic Scaffolds.

Authors:  David A Vargas; Rahul L Khade; Yong Zhang; Rudi Fasan
Journal:  Angew Chem Int Ed Engl       Date:  2019-06-24       Impact factor: 15.336

5.  3D-QSAR-Based Pharmacophore Modeling, Virtual Screening, and Molecular Dynamics Simulations for the Identification of Spleen Tyrosine Kinase Inhibitors.

Authors:  Vikas Kumar; Shraddha Parate; Amir Zeb; Pooja Singh; Gihwan Lee; Tae Sung Jung; Keun Woo Lee; Min Woo Ha
Journal:  Front Cell Infect Microbiol       Date:  2022-06-30       Impact factor: 6.073

Review 6.  Natural source, bioactivity and synthesis of benzofuran derivatives.

Authors:  Yu-Hang Miao; Yu-Heng Hu; Jie Yang; Teng Liu; Jie Sun; Xiao-Jing Wang
Journal:  RSC Adv       Date:  2019-09-02       Impact factor: 4.036

7.  Crystal structure of 2-(5-meth-oxy-1-benzo-furan-3-yl)acetic acid.

Authors:  Ramakrishna Gowda; K V Arjuna Gowda; M Keshava Reddy; Mahantesha Basanagouda
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-12-16

8.  Selectivity in the Elaboration of Bicyclic Borazarenes.

Authors:  Ayan Bhattacharjee; Geraint H M Davies; Borna Saeednia; Steven R Wisniewski; Gary A Molander
Journal:  Adv Synth Catal       Date:  2020-12-23       Impact factor: 5.837

9.  Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer.

Authors:  Wagdy M Eldehna; Rofaida Salem; Zainab M Elsayed; Tarfah Al-Warhi; Hamada R Knany; Rezk R Ayyad; Thamer Bin Traiki; Maha-Hamadien Abdulla; Rehan Ahmad; Hatem A Abdel-Aziz; Radwan El-Haggar
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

Review 10.  Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review.

Authors:  Ghadamali Khodarahmi; Parvin Asadi; Farshid Hassanzadeh; Elham Khodarahmi
Journal:  J Res Med Sci       Date:  2015-11       Impact factor: 1.852

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