Dual-pathway model of the human vestibulo-ocular reflex.

The purpose of the study was to investigate, evaluate and refine an existing dual-pathway VOR model by comparing the model responses with the responses of human subjects. Based on data of subjects' VOR responses, the physiological parameters and some gain constants in a dual-pathway model were adjusted to suit the human VOR data. As a result, the improved model can produce and exhibit the fundamental nystagmus patterns of human VOR responses to the head motions around a vertical axis for a wide range of frequencies and magnitudes. It was found that there is good agreement on quantitative analysis between the outcome of human VOR responses and the model output. Also, it was found that the quantitative analysis of slow-phase eye-movement data confirmed the previously published results.