Literature DB >> 26013639

Neurogenetics in Peru: clinical, scientific and ethical perspectives.

Mario Cornejo-Olivas1, Keren Espinoza-Huertas, Mario R Velit-Salazar, Diego Veliz-Otani, Indira Tirado-Hurtado, Miguel Inca-Martinez, Gustavo Silva-Paredes, Karina Milla-Neyra, Victoria Marca, Olimpio Ortega, Pilar Mazzetti.   

Abstract

Neurogenetics, the science that studies the genetic basis of the development and function of the nervous system, is a discipline of recent development in Peru, an emerging Latin American country. Herein, we review the clinical, scientific and ethical aspects regarding the development of this discipline, starting with the first molecular diagnosis of neurogenetic diseases, to family and population-based genetic association studies. Neurogenetics in Peru aims to better explain the epidemiology of monogenic and complex neurodegenerative disorders that will help in implementing public health policies for these disorders. The characterization of Peru and its health system, legal issues regarding rare diseases and the historical milestones in neurogenetics are also discussed.

Entities:  

Year:  2015        PMID： 26013639      PMCID： PMC4524878          DOI： 10.1007/s12687-015-0239-z

Source DB:  PubMed          Journal:  J Community Genet        ISSN： 1868-310X


  25 in total

Review 1.  Population stratification and spurious allelic association.

Authors:  Lon R Cardon; Lyle J Palmer
Journal:  Lancet       Date:  2003-02-15       Impact factor: 79.321

2.  Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways.

Authors:  Jeremy A Miller; Steve Horvath; Daniel H Geschwind
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-25       Impact factor: 11.205

3.  UN Declaration on the Rights of Indigenous Peoples.

Authors:  Carolyn Stephens; John Porter; Clive Nettleton; Ruth Willis
Journal:  Lancet       Date:  2007-11-24       Impact factor: 79.321

4.  Genetic services and testing in Brazil.

Authors:  Dafne Dain Gandelman Horovitz; Victor Evangelista de Faria Ferraz; Sulamis Dain; Antonia Paula Marques-de-Faria
Journal:  J Community Genet       Date:  2012-05-05

5.  Presymptomatic testing for neurogenetic diseases in Brazil: assessing who seeks and who follows through with testing.

Authors:  Caroline Santa Maria Rodrigues; Viviane Ziebell de Oliveira; Gabriela Camargo; Claudio Maria da Silva Osório; Raphael Machado de Castilhos; Maria Luiza Saraiva-Pereira; Lavínia Schuler-Faccini; Laura Bannach Jardim
Journal:  J Genet Couns       Date:  2011-06-30       Impact factor: 2.537

Review 6.  [Balancing risks and benefits of mammography screening for breast cancer: would you support its recommendation in Peruvian women?].

Authors:  Margarita Posso; Teresa Puig; Xavier Bonfill
Journal:  Rev Peru Med Exp Salud Publica       Date:  2015 Jan-Mar

Review 7.  Genome-scale neurogenetics: methodology and meaning.

Authors:  Steven A McCarroll; Guoping Feng; Steven E Hyman
Journal:  Nat Neurosci       Date:  2014-05-27       Impact factor: 24.884

8.  A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Authors: 
Journal:  Cell       Date:  1993-03-26       Impact factor: 41.582

9.  Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study.

Authors:  Natalia Acosta-Baena; Diego Sepulveda-Falla; Carlos Mario Lopera-Gómez; Mario César Jaramillo-Elorza; Sonia Moreno; Daniel Camilo Aguirre-Acevedo; Amanda Saldarriaga; Francisco Lopera
Journal:  Lancet Neurol       Date:  2011-02-04       Impact factor: 44.182

10.  Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders.

Authors:  Amit Lotan; Michaela Fenckova; Janita Bralten; Aet Alttoa; Luanna Dixson; Robert W Williams; Monique van der Voet
Journal:  Front Neurosci       Date:  2014-11-06       Impact factor: 4.677
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  4 in total

Review 1.  Neurology outreach clinic for Huntington disease in Peru: Lessons for neurodegenerative diseases.

Authors:  Anastasia Vishnevetsky; Maryenela Illanes-Manrique; Miguel Inca-Martinez; Karina Milla-Neyra; Elison Sarapura-Castro; Pilar Mazzetti; Mario Cornejo-Olivas
Journal:  Neurology       Date:  2018-07-06       Impact factor: 9.910

2.  The First Report of CADASIL in Peru: Olfactory Dysfunction on Initial Presentation.

Authors:  Anastasia Vishnevetsky; Miguel Inca-Martinez; Karina Milla-Neyra; Danny Moises Barrientos-Iman; Ivan Cornejo-Herrera; Carlos Cosentino; Mario Cornejo-Olivas
Journal:  eNeurologicalSci       Date:  2016-09-28

Review 3.  Genetics and genomics in Peru: Clinical and research perspective.

Authors:  Heinner Guio; Julio A Poterico; Kelly S Levano; Mario Cornejo-Olivas; Pilar Mazzetti; Gioconda Manassero-Morales; Manuel F Ugarte-Gil; Eduardo Acevedo-Vásquez; Milagros Dueñas-Roque; Alejandro Piscoya; Ricardo Fujita; Cesar Sanchez; Sandro Casavilca-Zambrano; Luis Jaramillo-Valverde; Yasser Sullcahuaman-Allende; Juan M Iglesias-Pedraz; Hugo Abarca-Barriga
Journal:  Mol Genet Genomic Med       Date:  2018-11       Impact factor: 2.183

4.  Economic burden of Huntington's disease in Peru.

Authors:  Gustavo Silva-Paredes; Rosa M Urbanos-Garrido; Miguel Inca-Martinez; Danielle Rabinowitz; Mario R Cornejo-Olivas
Journal:  BMC Health Serv Res       Date:  2019-12-30       Impact factor: 2.655
  4 in total

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