AIMS: The present report describes a novel coronary fractional flow reserve (FFR) system which allows FFR assessment using a rapid exchange microcatheter (RXi). METHODS AND RESULTS: The RXi microcatheter is compatible with standard 0.014" coronary guidewires facilitating lesion negotiation and FFR assessment in a wide range of coronary anatomies. In case of serial lesions, a microcatheter would have the important advantage of allowing multiple pullbacks while maintaining wire access to the vessel. The RXi is a fibre-optic sensor technology-based device. This technology might allow reduction in signal drift. The RXi microcatheter's fibre-optic sensor is located 5 mm from the distal tip. The microcatheter profile at the sensor site is 0.027"0.036". The segment of the catheter which is intended to reside within the target lesion is proximal to the sensor and has dimensions decreased to 0.020"0.025"; these dimensions are comparable to a 0.022" circular-shaped wire. CONCLUSIONS: The RXi microcatheter FFR system represents a novel technology that could allow easier lesion negotiation, maintaining guidewire position, facilitating pullbacks for assessment of serial lesions and simplifying the obtainment of post-intervention FFR measurements. The optical sensing technology could additionally result in less signal drift. Further investigations are required to evaluate the clinical value of this technology fully.
AIMS: The present report describes a novel coronary fractional flow reserve (FFR) system which allows FFR assessment using a rapid exchange microcatheter (RXi). METHODS AND RESULTS: The RXi microcatheter is compatible with standard 0.014" coronary guidewires facilitating lesion negotiation and FFR assessment in a wide range of coronary anatomies. In case of serial lesions, a microcatheter would have the important advantage of allowing multiple pullbacks while maintaining wire access to the vessel. The RXi is a fibre-optic sensor technology-based device. This technology might allow reduction in signal drift. The RXi microcatheter's fibre-optic sensor is located 5 mm from the distal tip. The microcatheter profile at the sensor site is 0.027"0.036". The segment of the catheter which is intended to reside within the target lesion is proximal to the sensor and has dimensions decreased to 0.020"0.025"; these dimensions are comparable to a 0.022" circular-shaped wire. CONCLUSIONS: The RXi microcatheter FFR system represents a novel technology that could allow easier lesion negotiation, maintaining guidewire position, facilitating pullbacks for assessment of serial lesions and simplifying the obtainment of post-intervention FFR measurements. The optical sensing technology could additionally result in less signal drift. Further investigations are required to evaluate the clinical value of this technology fully.
Authors: K Masdjedi; L J C van Zandvoort; T Neleman; I Kardys; J Ligthart; W K Den Dekker; R Diletti; F Zijlstra; N M Van Mieghem; J Daemen Journal: Neth Heart J Date: 2022-04-07 Impact factor: 2.854
Authors: Henry Seligman; Matthew J Shun-Shin; Anushkumar Vasireddy; Christopher Cook; Yousif Y Ahmad; James Howard; Sayan Sen; Rasha Al-Lamee; Sukhjinder Nijjer; Daniel Chamie; Justin Davies; Jamil Mayet; Darrel P Francis; Ricardo Petraco Journal: Open Heart Date: 2019-03-25
Authors: Roberto Diletti; Kaneshka Masdjedi; Joost Daemen; Laurens J C van Zandvoort; Tara Neleman; Jeroen Wilschut; Wijnand K Den Dekker; Rutger J van Bommel; Miguel Lemmert; Isabella Kardys; Paul Cummins; Peter de Jaegere; Felix Zijlstra; Nicolas M Van Mieghem Journal: Circ Cardiovasc Interv Date: 2021-03-09 Impact factor: 6.546
Authors: William F Fearon; Jeffrey W Chambers; Arnold H Seto; Ian J Sarembock; Ganesh Raveendran; Charlotte Sakarovitch; Lingyao Yang; Manisha Desai; Allen Jeremias; Matthew J Price Journal: Circ Cardiovasc Interv Date: 2017-12 Impact factor: 6.546