Literature DB >> 26012636

Aggregation and asymptotic analysis of an SI-epidemic model for heterogeneous populations.

V M Veliov1, A Widder2.   

Abstract

The paper investigates a version of a simple epidemiological model involving only susceptible and infected individuals, where the heterogeneity of the population with respect to susceptibility/infectiousness is taken into account. A comprehensive analysis of the asymptotic behaviour of the disease is given, based on an explicit aggregation of the model. The results are compared with those of a homogeneous version of the model to highlight the influence of the heterogeneity on the asymptotics. Moreover, the performed analysis reveals in which cases incomplete information about the heterogeneity of the population is sufficient in order to determine the long-run outcome of the disease. Numerical simulation is used to emphasize that, for a given level of prevalence, the evolution of the disease under the influence of heterogeneity may in the long run qualitatively differ from the one 'predicted' by the homogeneous model. Furthermore, it is shown that, in a closed population, the indicator for the survival of the population is in the presence of heterogeneity distinct from the basic reproduction number. © The authors 2015. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

Entities:  

Keywords:  SI model; heterogeneous epidemiological models; mathematical epidemiology

Mesh:

Year:  2015        PMID: 26012636     DOI: 10.1093/imammb/dqv018

Source DB:  PubMed          Journal:  Math Med Biol        ISSN: 1477-8599            Impact factor:   1.854


  1 in total

1.  Set-membership estimations for the evolution of infectious diseases in heterogeneous populations.

Authors:  Tsvetomir Tsachev; Vladimir M Veliov; Andreas Widder
Journal:  J Math Biol       Date:  2016-09-07       Impact factor: 2.259

  1 in total

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