Literature DB >> 26011984

Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation.

C Chidananda, K Y Vasantha, A P Sattur.   

Abstract

Sclerotiorin, isolated from the fermented broth of Penicillium frequentans, exhibited potent inhibition against human polymorphonuclear leukocytes 5-lipoxygenase and human platelet aggregation with a half maximal value 36 μM and 250 μM, respectively. Further, the Ames test has demonstrated the sclerotiorin to be non-mutagenic.

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Year:  2015        PMID： 26011984

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN： 0019-5189            Impact factor:   0.818


  2 in total

1.  Pollution of mycological surfaces in hospital emergency departments correlates positively with blood NKT CD3(+) 16(+) 56(+) and negatively with CD4(+) cell levels of their staff.

Authors:  Milena Suska; Sławomir Lewicki; Anna Kiepura; Izabela Winnicka; Paweł Leszczyński; Agata Bielawska-Drózd; Piotr Cieślik; Leszek Kubiak; Daria Depczyńska; Aleksandra Brewczyńska; Ewa Skopińska-Różewska; Janusz Kocik
Journal:  Cent Eur J Immunol       Date:  2016-03-24       Impact factor: 2.085

2.  Negative correlation between mycological surfaces pollution in hospital emergency departments and blood monocytes phagocytosis of healthcare workers.

Authors:  Sławomir Lewicki; Agata Bielawska-Drózd; Izabela Winnicka; Paweł Leszczyński; Piotr Cieślik; Teresa Korniłłowicz-Kowalska; Justyna Bohacz; Jolanta Jaroszuk-Ściseł; Ewa Skopińska-Różewska; Janusz Kocik
Journal:  Cent Eur J Immunol       Date:  2015-10-15       Impact factor: 2.085
  2 in total

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