Literature DB >> 26011968

Ten-year etiologic review of Chinese children hospitalized for pediatric cataracts.

Zixun Song, Daixin Zhao, Cancan Lv, Wei Pu, Wei Xiao.   

Abstract

PURPOSE: Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.
METHODS: Medical records accrued over a 10-year period (from August, 2003 to July, 2013) at Shengjing Hospital of China Medical University were reviewed retrospectively, identifying all patients treated for various subtypes of pediatric cataract. A database with 367 subjects under 14 years of age (598, including second-round surgeries) was generated.
RESULTS: Of this cohort (n = 367; males: 232, 63.2%; females: 135, 36.8%), 200 patients (54.5%) had bilateral cataracts, and 258 (70.3%) were under 3 years of age. In all age groups and in all subtypes of pediatric cataract, males were most commonly affected. Congenital cataract was the most prevalent subtype, accounting for 296 patients (80.7%). Most congenital cataracts were associated with other ocular or systemic abnormalities; and in 48 patients (16.22%), they were hereditary. Traumatic cataract was the most common subtype (85.92%) of acquired cataract. The few instances of cataracts due to steroids (n = 3) or to metabolic disorders (n = 2) occurred in males and involved both eyes.
CONCLUSION: The majority of pediatric cataracts in this patient population were congenital in nature. A significant lag in ophthalmologic evaluation of Chinese infants was evident and should be addressed by educating both children and parents on risk factors for cataract development. Regular assessments are especially important in children subjected to long-term systemic steroid treatments.

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Year:  2014        PMID: 26011968

Source DB:  PubMed          Journal:  Eye Sci


  4 in total

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Journal:  BMC Ophthalmol       Date:  2017-05-19       Impact factor: 2.209

2.  Outcome of Pediatric Cataract Surgeries in a Tertiary Center in Switzerland.

Authors:  Sarah Claudia Ambroz; Marc Töteberg-Harms; James V M Hanson; Jens Funk; Daniel Barthelmes; Christina Gerth-Kahlert
Journal:  J Ophthalmol       Date:  2018-02-25       Impact factor: 1.909

3.  Case Report: A Novel Mutation in the CRYGD Gene Causing Congenital Cataract Associated with Nystagmus in a Chinese Family.

Authors:  Yunxia Gao; Xiang Ren; Xiangyu Fu; Yu Lin; Lirong Xiao; Xiaoyue Wang; Naihong Yan; Ming Zhang
Journal:  Front Genet       Date:  2022-02-10       Impact factor: 4.599

4.  A novel mutation in the CRYAA gene associated with congenital cataract and microphthalmia in a Chinese family.

Authors:  Zixun Song; Nuo Si; Wei Xiao
Journal:  BMC Med Genet       Date:  2018-10-19       Impact factor: 2.103

  4 in total

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