Literature DB >> 26011928

Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment.

Hanqing Liu, Zhigang Tu, Fan Feng, Haifeng Shi, Keping Chen, Ximing Xu.   

Abstract

A virosome is an innovative hybrid drug delivery system with advantages of both viral and non-viral vectors. Studies have shown that a virosome can carry various biologically active molecules, such as nucleic acids, peptides, proteins and small organic molecules. Targeted drug delivery using virosome-based systems can be achieved through surface modifications of virosomes. A number of virosome-based prophylactic and therapeutic products with high safety profiles are currently available in the market. Cancer treatment is a big battlefield for virosome-based drug delivery systems. This review provides an overview of the general concept, preparation procedures, working mechanisms, preclinical studies and clinical applications of virosomes in cancer treatment.

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Year:  2015        PMID： 26011928     DOI： 10.1515/acph-2015-0019

Source DB:  PubMed          Journal:  Acta Pharm        ISSN： 1330-0075            Impact factor:   2.230


  11 in total

Review 1.  Advances in Infectious Disease Vaccine Adjuvants.

Authors:  Jingyi Fan; Shengbin Jin; Lachlan Gilmartin; Istvan Toth; Waleed M Hussein; Rachel J Stephenson
Journal:  Vaccines (Basel)       Date:  2022-07-13

Review 2.  Synthetic cells in biomedical applications.

Authors:  Wakana Sato; Tomasz Zajkowski; Felix Moser; Katarzyna P Adamala
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2021-11-01

Review 3.  Nanoparticles: augmenting tumor antigen presentation for vaccine and immunotherapy treatments of cancer.

Authors:  Charles B Chesson; Andrew Zloza
Journal:  Nanomedicine (Lond)       Date:  2017-11-03       Impact factor: 5.307

4.  Targeted Drug Delivery in Lipid-like Nanocages and Extracellular Vesicles.

Authors:  A V Sokolov; N N Kostin; L A Ovchinnikova; Y A Lomakin; A A Kudriaeva
Journal:  Acta Naturae       Date:  2019 Apr-Jun       Impact factor: 1.845

Review 5.  Promising Adjuvants and Platforms for Influenza Vaccine Development.

Authors:  Wandi Zhu; Chunhong Dong; Lai Wei; Bao-Zhong Wang
Journal:  Pharmaceutics       Date:  2021-01-07       Impact factor: 6.321

Review 6.  Delivery of cancer therapies by synthetic and bio-inspired nanovectors.

Authors:  Tina Briolay; Tacien Petithomme; Morgane Fouet; Nelly Nguyen-Pham; Christophe Blanquart; Nicolas Boisgerault
Journal:  Mol Cancer       Date:  2021-03-24       Impact factor: 27.401

Review 7.  Cancer Vaccines: Adjuvant Potency, Importance of Age, Lifestyle, and Treatments.

Authors:  Stefania Cuzzubbo; Sara Mangsbo; Divya Nagarajan; Kinana Habra; Alan Graham Pockley; Stephanie E B McArdle
Journal:  Front Immunol       Date:  2021-02-17       Impact factor: 7.561

Review 8.  Virosome-based nanovaccines; a promising bioinspiration and biomimetic approach for preventing viral diseases: A review.

Authors:  Khatereh Asadi; Ahmad Gholami
Journal:  Int J Biol Macromol       Date:  2021-04-16       Impact factor: 6.953

9.  Preparation and characterization of nanocurcumin based hybrid virosomes as a drug delivery vehicle with enhanced anticancerous activity and reduced toxicity.

Authors:  Varun Kumar; Ramesh Kumar; V K Jain; Suman Nagpal
Journal:  Sci Rep       Date:  2021-01-11       Impact factor: 4.379

Review 10.  Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications.

Authors:  Christopher D Spicer; Coline Jumeaux; Bakul Gupta; Molly M Stevens
Journal:  Chem Soc Rev       Date:  2018-05-21       Impact factor: 54.564
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