Construction of a reusable multi-enzyme supramolecular device via disulfide bond locking.

A strategy for constructing a reusable multi-enzyme supramolecular device was developed by reprogramming protein-protein interactions and disulfide bond locking. The resultant multi-enzyme supramolecular device demonstrated good reusability, and approximately 80% of its initial catalytic activity was retained even after eight cycles of reuse.