Swann Arp Adams1, Michael D Wirth2, Samira Khan3, E Angela Murphy4, Sue P Heiney5, Lisa C Davis6, Briana Davis7, Ruby F Drayton8, Thomas G Hurley9, Steven N Blair10, James R Hébert11. 1. College of Nursing and the Department of Epidemiology and Biostatistics, Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA. Electronic address: swann.adams@sc.edu. 2. Department of Epidemiology and Biostatistics, Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA. Electronic address: wirthm@mailbox.sc.edu. 3. Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29207, USA. Electronic address: khans@mailbox.sc.edu. 4. Department of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209, USA. Electronic address: angela.murphy@uscmed.sc.edu. 5. College of Nursing, University of South Carolina, Columbia, SC, USA. Electronic address: heineys@mailbox.sc.edu. 6. Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA. Electronic address: ldavis@mailbox.sc.edu. 7. Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA. Electronic address: BRIANAD@mailbox.sc.edu. 8. Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA. Electronic address: draytonr@mailbox.sc.edu. 9. Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA. Electronic address: thurley@mailbox.sc.edu. 10. Departments of Exercise Science and Epidemiology/Biostatistics, Arnold School of Public Health, University of South Carolina, 921 Assembly Street, Columbia, SC 29208, USA. Electronic address: sblair@mailbox.sc.edu. 11. Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA; Statewide Cancer Prevention & Control Program, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA. Electronic address: jhebert@sc.edu.
Abstract
OBJECTIVE: Regular physical activity can reduce systemic inflammation and, thereby, the burden of chronic inflammatory-related conditions. This study examined whether regular physical activity, measured subjectively (Rapid Assessment of Physical Activity [RAPA]) and objectively (Bodymedia's SenseWear® activity monitor [SWA]), is associated with inflammatory or glycemic control markers. METHODS: Subjects were 345 participants of the Healthy Eating and Active Living in the Spirit (HEALS) lifestyle intervention among African American (AA) churches in South Carolina from 2009 to 2012. Linear regression analyses were performed to assess the relationship between both subjectively and objectively measured physical activity and inflammatory markers including high sensitivity C-reactive protein (CRP), interleukin-6 (IL-6), and glycosylated hemoglobin (HbA1c). RESULTS: Those who participated in regular physical activity (from RAPA) had lower CRP values compared to those who were sedentary (2.3 vs. 3.8mg/L, p<0.01). Lower levels of CRP or IL-6 were observed among those in the highest quartile of active energy expenditure (CRP: 2.0 vs. 3.6 mg/L, p=0.01) or moderate-vigorous physical activity minutes (CRP=1.7 vs. 4.5mg/L, p<0.01; IL-6=1.5 vs. 2.1pg/mL, p=0.01) compared to their lowest respective quartiles as measured by the SWA. CONCLUSION: Physical activity may improve chronic inflammation, which is a primary pathophysiological mechanism for numerous chronic disorders, especially among minority populations.
OBJECTIVE: Regular physical activity can reduce systemic inflammation and, thereby, the burden of chronic inflammatory-related conditions. This study examined whether regular physical activity, measured subjectively (Rapid Assessment of Physical Activity [RAPA]) and objectively (Bodymedia's SenseWear® activity monitor [SWA]), is associated with inflammatory or glycemic control markers. METHODS: Subjects were 345 participants of the Healthy Eating and Active Living in the Spirit (HEALS) lifestyle intervention among African American (AA) churches in South Carolina from 2009 to 2012. Linear regression analyses were performed to assess the relationship between both subjectively and objectively measured physical activity and inflammatory markers including high sensitivity C-reactive protein (CRP), interleukin-6 (IL-6), and glycosylated hemoglobin (HbA1c). RESULTS: Those who participated in regular physical activity (from RAPA) had lower CRP values compared to those who were sedentary (2.3 vs. 3.8mg/L, p<0.01). Lower levels of CRP or IL-6 were observed among those in the highest quartile of active energy expenditure (CRP: 2.0 vs. 3.6 mg/L, p=0.01) or moderate-vigorous physical activity minutes (CRP=1.7 vs. 4.5mg/L, p<0.01; IL-6=1.5 vs. 2.1pg/mL, p=0.01) compared to their lowest respective quartiles as measured by the SWA. CONCLUSION: Physical activity may improve chronic inflammation, which is a primary pathophysiological mechanism for numerous chronic disorders, especially among minority populations.
Authors: Nasar U Ahmed; Gary L Smith; Ann M Flores; Rubens J Pamies; Hyacinth R C Mason; Kristy F Woods; Steven C Stain Journal: Ethn Dis Date: 2005 Impact factor: 1.847
Authors: Amit Khera; Darren K McGuire; Sabina A Murphy; Harold G Stanek; Sandeep R Das; Wanpen Vongpatanasin; Frank H Wians; Scott M Grundy; James A de Lemos Journal: J Am Coll Cardiol Date: 2005-08-02 Impact factor: 24.094
Authors: Tari D Topolski; James LoGerfo; Donald L Patrick; Barbara Williams; Julie Walwick; Marsha B Patrick Journal: Prev Chronic Dis Date: 2006-09-15 Impact factor: 2.830
Authors: Daria M McMahon; James B Burch; James R Hébert; James W Hardin; Jiajia Zhang; Michael D Wirth; Shawn D Youngstedt; Nitin Shivappa; Steven J Jacobsen; Bette Caan; Stephen K Van Den Eeden Journal: Ann Epidemiol Date: 2018-11-02 Impact factor: 3.797
Authors: Malcolm Bevel; Oluwole A Babatunde; Sue P Heiney; Heather M Brandt; Michael D Wirth; Thomas G Hurley; Samira Khan; Hiluv Johnson; Cassandra M Wineglass; Tatiana Y Warren; E Angela Murphy; Erica Sercy; Amanda S Thomas; James R Hébert; Swann Arp Adams Journal: Ethn Dis Date: 2018-04-26 Impact factor: 1.847
Authors: Barbara J Nicklas; Daniel P Beavers; Shannon L Mihalko; Gary D Miller; Richard F Loeser; Stephen P Messier Journal: J Gerontol A Biol Sci Med Sci Date: 2016-07-05 Impact factor: 6.053
Authors: Hiba AbouAssi; Margery A Connelly; Lori A Bateman; K Noelle Tune; Janet L Huebner; Virginia B Kraus; Deborah A Winegar; James D Otvos; William E Kraus; Kim M Huffman Journal: Lipids Health Dis Date: 2017-02-10 Impact factor: 3.876