Literature DB >> 26007211

Lysosomes to combat Parkinson's disease.

Ole Isacson1.   

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Year:  2015        PMID： 26007211     DOI： 10.1038/nn.4027

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


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  15 in total

1.  Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection.

Authors:  Chee Yeun Chung; Hyemyung Seo; Kai Christian Sonntag; Andrew Brooks; Ling Lin; Ole Isacson
Journal:  Hum Mol Genet       Date:  2005-05-11       Impact factor: 6.150

2.  Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies.

Authors:  Joseph R Mazzulli; You-Hai Xu; Ying Sun; Adam L Knight; Pamela J McLean; Guy A Caldwell; Ellen Sidransky; Gregory A Grabowski; Dimitri Krainc
Journal:  Cell       Date:  2011-06-23       Impact factor: 41.582

3.  The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.

Authors:  Chee Yeun Chung; Pawel Licznerski; Kambiz N Alavian; Antonio Simeone; Zhicheng Lin; Eden Martin; Jeffery Vance; Ole Isacson
Journal:  Brain       Date:  2010-06-23       Impact factor: 13.501

4.  Pathogenic lysosomal depletion in Parkinson's disease.

Authors:  Benjamin Dehay; Jordi Bové; Natalia Rodríguez-Muela; Celine Perier; Ariadna Recasens; Patricia Boya; Miquel Vila
Journal:  J Neurosci       Date:  2010-09-15       Impact factor: 6.167

5.  Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.

Authors:  Ariadna Laguna; Nicoletta Schintu; André Nobre; Alexandra Alvarsson; Nikolaos Volakakis; Jesper Kjaer Jacobsen; Marta Gómez-Galán; Elena Sopova; Eliza Joodmardi; Takashi Yoshitake; Qiaolin Deng; Jan Kehr; Johan Ericson; Per Svenningsson; Oleg Shupliakov; Thomas Perlmann
Journal:  Nat Neurosci       Date:  2015-04-27       Impact factor: 24.884

6.  TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.

Authors:  Mickael Decressac; Bengt Mattsson; Pia Weikop; Martin Lundblad; Johan Jakobsson; Anders Björklund
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-22       Impact factor: 11.205

Review 7.  The role of autophagy in neurodegenerative disease.

Authors:  Ralph A Nixon
Journal:  Nat Med       Date:  2013-08-06       Impact factor: 53.440

8.  Progressive decline of glucocerebrosidase in aging and Parkinson's disease.

Authors:  Emily M Rocha; Gaynor A Smith; Eric Park; Hongmei Cao; Eilish Brown; Penelope Hallett; Ole Isacson
Journal:  Ann Clin Transl Neurol       Date:  2015-02-06       Impact factor: 4.511

9.  Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease.

Authors:  Sian E Davies; Penelope J Hallett; Thomas Moens; Gaynor Smith; Emily Mangano; Hyoung Tae Kim; Alfred L Goldberg; Ji-Long Liu; Ole Isacson; George K Tofaris
Journal:  Neurobiol Dis       Date:  2013-12-31       Impact factor: 5.996

10.  Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains.

Authors:  Matthew E Gegg; Derek Burke; Simon J R Heales; J Mark Cooper; John Hardy; Nicholas W Wood; Anthony H V Schapira
Journal:  Ann Neurol       Date:  2012-09       Impact factor: 10.422
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  1 in total

1.  Integrated molecular landscape of Parkinson's disease.

Authors:  J E Visser; G Poelmans; C J H M Klemann; G J M Martens; M Sharma; M B Martens; O Isacson; T Gasser
Journal:  NPJ Parkinsons Dis       Date:  2017-04-10
  1 in total

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