Objective: The aim of the present study was to investigate the specificity of inhibition, working memory (WM), and reaction time variability (RTV) in relation to symptoms of ADHD and autism spectrum disorder (ASD). Method: A community-based sample of schoolchildren aged 7 to 9 years (N = 200) completed tasks designed to measure inhibition, WM, and RTV. Results: All neuropsychological functions were related to symptoms of both ADHD and ASD. The results from regression analyses showed that inhibition and RTV were related specifically to ADHD symptoms when controlling for symptoms of ASD. Regarding WM, no specific association with either symptom domain was evident after controlling for the other. Furthermore, independent contributions of inhibition and RTV were found in relation to ADHD symptoms after controlling for ASD symptoms. Conclusion: The present study underscores the relevance of controlling for ADHD symptoms when examining ASD symptoms in relation to neuropsychological functions.
Objective: The aim of the present study was to investigate the specificity of inhibition, working memory (WM), and reaction time variability (RTV) in relation to symptoms of ADHD and autism spectrum disorder (ASD). Method: A community-based sample of schoolchildren aged 7 to 9 years (N = 200) completed tasks designed to measure inhibition, WM, and RTV. Results: All neuropsychological functions were related to symptoms of both ADHD and ASD. The results from regression analyses showed that inhibition and RTV were related specifically to ADHD symptoms when controlling for symptoms of ASD. Regarding WM, no specific association with either symptom domain was evident after controlling for the other. Furthermore, independent contributions of inhibition and RTV were found in relation to ADHD symptoms after controlling for ASD symptoms. Conclusion: The present study underscores the relevance of controlling for ADHD symptoms when examining ASD symptoms in relation to neuropsychological functions.
Authors: Martine Hoogman; Daan van Rooij; Marieke Klein; Premika Boedhoe; Iva Ilioska; Ting Li; Yash Patel; Merel C Postema; Yanli Zhang-James; Evdokia Anagnostou; Celso Arango; Guillaume Auzias; Tobias Banaschewski; Claiton H D Bau; Marlene Behrmann; Mark A Bellgrove; Daniel Brandeis; Silvia Brem; Geraldo F Busatto; Sara Calderoni; Rosa Calvo; Francisco X Castellanos; David Coghill; Annette Conzelmann; Eileen Daly; Christine Deruelle; Ilan Dinstein; Sarah Durston; Christine Ecker; Stefan Ehrlich; Jeffery N Epstein; Damien A Fair; Jacqueline Fitzgerald; Christine M Freitag; Thomas Frodl; Louise Gallagher; Eugenio H Grevet; Jan Haavik; Pieter J Hoekstra; Joost Janssen; Georgii Karkashadze; Joseph A King; Kerstin Konrad; Jonna Kuntsi; Luisa Lazaro; Jason P Lerch; Klaus-Peter Lesch; Mario R Louza; Beatriz Luna; Paulo Mattos; Jane McGrath; Filippo Muratori; Clodagh Murphy; Joel T Nigg; Eileen Oberwelland-Weiss; Ruth L O'Gorman Tuura; Kirsten O'Hearn; Jaap Oosterlaan; Mara Parellada; Paul Pauli; Kerstin J Plessen; J Antoni Ramos-Quiroga; Andreas Reif; Liesbeth Reneman; Alessandra Retico; Pedro G P Rosa; Katya Rubia; Philip Shaw; Tim J Silk; Leanne Tamm; Oscar Vilarroya; Susanne Walitza; Neda Jahanshad; Stephen V Faraone; Clyde Francks; Odile A van den Heuvel; Tomas Paus; Paul M Thompson; Jan K Buitelaar; Barbara Franke Journal: Hum Brain Mapp Date: 2020-05-18 Impact factor: 5.038