Literature DB >> 26005029

Exact solutions for the selection-mutation equilibrium in the Crow-Kimura evolutionary model.

Yuri S Semenov1, Artem S Novozhilov2.   

Abstract

We reformulate the eigenvalue problem for the selection-mutation equilibrium distribution in the case of a haploid asexually reproduced population in the form of an equation for an unknown probability generating function of this distribution. The special form of this equation in the infinite sequence limit allows us to obtain analytically the steady state distributions for a number of particular cases of the fitness landscape. The general approach is illustrated by examples; theoretical findings are compared with numerical calculations.
Copyright © 2015. Published by Elsevier Inc.

Keywords:  Crow–Kimura model; Error threshold; Quasispecies model; Selection–mutation equilibrium; Single peaked landscape

Mesh:

Year:  2015        PMID: 26005029     DOI: 10.1016/j.mbs.2015.05.002

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


  2 in total

1.  Generalized quasispecies model on finite metric spaces: isometry groups and spectral properties of evolutionary matrices.

Authors:  Yuri S Semenov; Artem S Novozhilov
Journal:  J Math Biol       Date:  2018-09-05       Impact factor: 2.259

2.  A DNA Damage-Repair Dynamic Model for HRS/IRR Effects of C.elegans Induced by Neutron Irradiation.

Authors:  Guangyan Feng; Lianxin Zhang; Zhanguo Yang; Yong Zhang; Siwei Zhang; Taosheng Li; Zhao Xu
Journal:  Dose Response       Date:  2021-03-11       Impact factor: 2.658

  2 in total

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