UNLABELLED: In this study, we investigated the early and long-term results of conventional aortic valve replacement (AVR) in very old patients. METHODS: Seventy-five patients with aortic stenosis underwent conventional AVR for patients aged 80 years.We examined early death and major adverse cardiovascular and cerebrovascular event (MACCE). RESULTS: The operative mortality was 0% for isolated AVR and 19.2% for concomitant surgery. The postoperative survival rate and MACCE free-rate were no significant differences between the isolated AVR and the concomitant surgery. Univariate analysis confirmed that cardiac dysfunction, severe chronic kidney disease (CKD), hemodialysis, + coronary artery bypass grafting, and norepinephrine use were risk factor of early death. Univariate analysis confirmed that severe CKD, BNP >1000 pg/ml, aortic cross clamping time (ACCT) >180 min, and non-use carperitide and multivariate analysis confirmed that ACCT >180 min, and non-use carperitide were risk factor of MACCE. CONCLUSIONS: This study showed that the results of conventional AVR in very old patients were not satisfactory. However, the results obtained with isolated AVR were favorable with no operative deaths. The present study demonstrated that preoperative cardiac function, preoperative renal function, and operative factors have an important impact on early mortality and MACCE.
UNLABELLED: In this study, we investigated the early and long-term results of conventional aortic valve replacement (AVR) in very old patients. METHODS: Seventy-five patients with aortic stenosis underwent conventional AVR for patients aged 80 years.We examined early death and major adverse cardiovascular and cerebrovascular event (MACCE). RESULTS: The operative mortality was 0% for isolated AVR and 19.2% for concomitant surgery. The postoperative survival rate and MACCE free-rate were no significant differences between the isolated AVR and the concomitant surgery. Univariate analysis confirmed that cardiac dysfunction, severe chronic kidney disease (CKD), hemodialysis, + coronary artery bypass grafting, and norepinephrine use were risk factor of early death. Univariate analysis confirmed that severe CKD, BNP >1000 pg/ml, aortic cross clamping time (ACCT) >180 min, and non-use carperitide and multivariate analysis confirmed that ACCT >180 min, and non-use carperitide were risk factor of MACCE. CONCLUSIONS: This study showed that the results of conventional AVR in very old patients were not satisfactory. However, the results obtained with isolated AVR were favorable with no operative deaths. The present study demonstrated that preoperative cardiac function, preoperative renal function, and operative factors have an important impact on early mortality and MACCE.
Authors: Martine Gilard; Hélène Eltchaninoff; Bernard Iung; Patrick Donzeau-Gouge; Karine Chevreul; Jean Fajadet; Pascal Leprince; Alain Leguerrier; Michel Lievre; Alain Prat; Emmanuel Teiger; Thierry Lefevre; Dominique Himbert; Didier Tchetche; Didier Carrié; Bernard Albat; Alain Cribier; Gilles Rioufol; Arnaud Sudre; Didier Blanchard; Frederic Collet; Pierre Dos Santos; Nicolas Meneveau; Ashok Tirouvanziam; Christophe Caussin; Philippe Guyon; Jacques Boschat; Herve Le Breton; Frederic Collart; Remi Houel; Stephane Delpine; Geraud Souteyrand; Xavier Favereau; Patrick Ohlmann; Vincent Doisy; Gilles Grollier; Antoine Gommeaux; Jean-Philippe Claudel; Francois Bourlon; Bernard Bertrand; Eric Van Belle; Marc Laskar Journal: N Engl J Med Date: 2012-05-03 Impact factor: 91.245
Authors: Anna Kwiecień; Tomasz Hrapkowicz; Krzysztof Filipiak; Roman Przybylski; Marcin Kaczmarczyk; Anetta Kowalczuk; Marian Zembala Journal: Kardiochir Torakochirurgia Pol Date: 2018-09-24
Authors: Farid Foroutan; Gordon H Guyatt; Kathleen O'Brien; Eva Bain; Madeleine Stein; Sai Bhagra; Daegan Sit; Rakhshan Kamran; Yaping Chang; Tahira Devji; Hassan Mir; Veena Manja; Toni Schofield; Reed A Siemieniuk; Thomas Agoritsas; Rodrigo Bagur; Catherine M Otto; Per O Vandvik Journal: BMJ Date: 2016-09-28