Literature DB >> 26003375

Platelet miRNAs and cardiovascular diseases.

Eduardo Fuentes1, Iván Palomo2, Marcelo Alarcón3.   

Abstract

Activated platelets play a critical role in the acute complications of atherosclerosis that cause life-threatening ischemic events at late stages of the disease. The miRNAs are a novel class of small, non-coding RNAs that play a significant role in both inflammatory and cardiovascular diseases. The miRNAs are known to be present in platelets and exert important regulatory functions. Here we systematically examine the genes that are regulated by platelet miRNAs (miRNA-223,miRNA-126,miRNA-21, miRNA-24 and miRNA-197) and the association with cardiovascular disease risks. Platelet-secreted miRNAs could be novel biomarkers associated with cardiovascular diseases.

Entities:  

Keywords:  Cardiovascular diseases; Genes; Platelet; miRNAs

Mesh:

Substances:

Year:  2015        PMID: 26003375     DOI: 10.1016/j.lfs.2015.04.016

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  13 in total

Review 1.  Effects of P2Y12 receptor antagonists beyond platelet inhibition--comparison of ticagrelor with thienopyridines.

Authors:  Sven Nylander; Rainer Schulz
Journal:  Br J Pharmacol       Date:  2016-02-24       Impact factor: 8.739

2.  Characterization of surface antigens of reticulated immature platelets.

Authors:  Adi Lador; Dorit Leshem-Lev; Galia Spectre; Aryeh Abelow; Ran Kornowski; Eli I Lev
Journal:  J Thromb Thrombolysis       Date:  2017-10       Impact factor: 2.300

Review 3.  Insights Into Platelet-Derived MicroRNAs in Cardiovascular and Oncologic Diseases: Potential Predictor and Therapeutic Target.

Authors:  Qianru Leng; Jie Ding; Meiyan Dai; Lei Liu; Qing Fang; Dao Wen Wang; Lujin Wu; Yan Wang
Journal:  Front Cardiovasc Med       Date:  2022-06-09

4.  Predictive value of miRNA-126 on in-stent restenosis in patients with coronary heart disease: A protocol for meta-analysis and bioinformatics analysis.

Authors:  Xianke Qiu; Jun Wang; Zhongping Shi; Xiaojun Ji; Yiwei Huang; Haiyue Dai
Journal:  Medicine (Baltimore)       Date:  2021-06-04       Impact factor: 1.817

Review 5.  Platelets miRNA as a Prediction Marker of Thrombotic Episodes.

Authors:  Michal Bijak; Malgorzata Dzieciol; Joanna Rywaniak; Joanna Saluk; Marzenna Zielinska
Journal:  Dis Markers       Date:  2016-11-30       Impact factor: 3.434

Review 6.  Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies.

Authors:  Raminderjit Kaur; Manpreet Kaur; Jatinder Singh
Journal:  Cardiovasc Diabetol       Date:  2018-08-31       Impact factor: 9.951

7.  Platelets of Healthy Origins Promote Functional Improvement of Atherosclerotic Endothelial Progenitor Cells.

Authors:  Nicoleta Alexandru; Florentina Safciuc; Alina Constantin; Miruna Nemecz; Gabriela Tanko; Alexandru Filippi; Emanuel Dragan; Elisabeta Bãdilã; Adriana Georgescu
Journal:  Front Pharmacol       Date:  2019-04-24       Impact factor: 5.810

8.  Hypertension Associated With Hyperlipidemia Induced Different MicroRNA Expression Profiles in Plasma, Platelets, and Platelet-Derived Microvesicles; Effects of Endothelial Progenitor Cell Therapy.

Authors:  Nicoleta Alexandru; Alina Constantin; Miruna Nemecz; Ioana Karla Comariţa; Alexandra Vîlcu; Anastasia Procopciuc; Gabriela Tanko; Adriana Georgescu
Journal:  Front Med (Lausanne)       Date:  2019-12-03

9.  Association of the Single Nucleotide Polymorphisms in microRNAs 130b, 200b, and 495 with Ischemic Stroke Susceptibility and Post-Stroke Mortality.

Authors:  Jinkwon Kim; Gun Ho Choi; Ki Han Ko; Jung Oh Kim; Seung Hun Oh; Young Seok Park; Ok Joon Kim; Nam Keun Kim
Journal:  PLoS One       Date:  2016-09-07       Impact factor: 3.240

Review 10.  The Potential Role of Platelet-Related microRNAs in the Development of Cardiovascular Events in High-Risk Populations, Including Diabetic Patients: A Review.

Authors:  Justyna Pordzik; Katarzyna Pisarz; Salvatore De Rosa; Axel Dyve Jones; Ceren Eyileten; Ciro Indolfi; Lukasz Malek; Marek Postula
Journal:  Front Endocrinol (Lausanne)       Date:  2018-03-20       Impact factor: 5.555

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