Literature DB >> 26002664

Giant pseudoangiomatous stromal hyperplasia presenting in the breast of a prepubertal child.

Tarig Abdelrahman1, Philippa Young2, Olexandra Kozyar3, Eleri Davies4, Stefan Dojcinov3, Robert E Mansel4.   

Abstract

Large benign lesions of the breasts are rare in children. We present a case of a 35 cm mass, weighing 2.7 kg in a 13-year-old girl with small developing breasts. Despite the enormity of the lesion, the patient managed to keep it concealed from her parents for 8 months. While initially suspicious of sarcoma a diagnosis of pseudoangiomatous stromal hyperplasia was suggested radiologically and confirmed histologically. Excision with reduction mammoplasty was performed, care taken not to disrupt the remaining breast tissue to facilitate future breast development. 18 months on, the cosmetic appearance of the breasts is good, with healthy underlying breast tissue developing. To the best of our knowledge this case is the largest documented breast tumour of this type in a patient of this age and illustrates the challenge of treating such tumours in the developing breast. 2015 BMJ Publishing Group Ltd.

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Mesh:

Year:  2015        PMID: 26002664      PMCID: PMC4442162          DOI: 10.1136/bcr-2014-206797

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

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Review 2.  Angiosarcoma after breast-conserving therapy.

Authors:  Alan T Monroe; Steven J Feigenberg; Nancy Price Mendenhall
Journal:  Cancer       Date:  2003-04-15       Impact factor: 6.860

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4.  MUC4 is a highly sensitive and specific marker for low-grade fibromyxoid sarcoma.

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5.  Pseudoangiomatous stromal hyperplasia of the breast in a 10-year-old girl.

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6.  Mammary angiosarcomas: imaging findings in 24 patients.

Authors:  Wei Tse Yang; Bryan T J Hennessy; Mark J Dryden; Vicente Valero; Kelly K Hunt; Savitri Krishnamurthy
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7.  Pseudoangiomatous stromal hyperplasia (PASH). A mammary stromal tumor with myofibroblastic differentiation.

Authors:  C M Powell; M L Cranor; P P Rosen
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8.  Tumoral pseudoangiomatous stromal hyperplasia of the breast.

Authors:  Stephanie M Wieman; Jeffrey Landercasper; Jeanne M Johnson; Richard L Ellis; Susan M Wester; Pamela J Lambert; Lauren A Ross
Journal:  Am Surg       Date:  2008-12       Impact factor: 0.688

9.  Pseudoangiomatous hyperplasia of mammary stroma.

Authors:  M F Vuitch; P P Rosen; R A Erlandson
Journal:  Hum Pathol       Date:  1986-02       Impact factor: 3.466

10.  Pseudoangiomatous stromal hyperplasia tumor: a clinical, radiologic and pathologic study of 26 cases.

Authors:  Marco Ferreira; Constance T Albarracin; Erika Resetkova
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  2 in total

1.  Tiger-Striped PASH: Recognition of a Unique Morphology Allows for a Zippered-Up Diagnosis of Pseudoangiomatous Stromal Hyperplasia of Breast.

Authors:  Mohamad Sakibuzzaman; Ryan W Kendziora; Toshi Ghosh; Malvika H Solanki; Amy Lynn Conners; Lisa J Ahlberg; Charles D Sturgis
Journal:  Case Rep Pathol       Date:  2021-12-26

2.  Pseudoangiomatous stromal hyperplasia of the breast: A case report.

Authors:  Sedigheh Tahmasebi; Atefeh Khorsand Rahim Zadeh; Vahid Zangouri; Majid Akrami; Masoumeh Ghoddusi Johari; Abdolrasoul Talei
Journal:  Clin Case Rep       Date:  2022-08-09
  2 in total

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