| Literature DB >> 26002494 |
S Clément1, M Gargiulo2, J Feingold3, A Durr4.
Abstract
Huntington's disease was the first adult onset neurological disease for which presymptomatic genetic testing became possible. It served as a model for the approach which constituted a radical change in medical practice and provided an important framework for multi-step, multidisciplinary, counselling for at risk persons. We will review the historical context of guidelines and good clinical practices, the experiences of our team which covers more than 20 years of presymptomatic testing for Huntington's disease in France, and explore the impact of the new French legislation for the future of presymptomatic testing of diseases for which neither preventive measures nor curative treatments are yet available.Entities:
Keywords: Family medical information; French legal obligations; Huntington's disease; Information de la parentèle; International recommendations; Maladie de Huntington; Obligations légales en France; Presymptomatic testing; Recommandations internationales; Test présymptomatique
Mesh：
Year: 2015 PMID： 26002494 DOI： 10.1016/j.neurol.2015.02.016
Source DB: PubMed Journal: Rev Neurol (Paris) ISSN： 0035-3787 Impact factor: 2.607