Dimitrios Kloukos1, Iosif Sifakakis2, Dimitra Voutsa3, Ioannis Doulis4, George Eliades5, Christos Katsaros6, Theodore Eliades7. 1. Department of Orthodontics and Dentofacial Orthopedics, Faculty of Medicine, University of Bern, Switzerland; 251 Air Force General Hospital, Athens, Greece. 2. Department of Orthodontics, School of Dentistry, University of Athens, Athens, Greece. 3. Environmental Pollution Control Laboratory, School of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece. 4. Department of Orthodontics, 251 Hellenic Air Force General Hospital, Athens, Greece. 5. Department of Biomaterials, School of Dentistry, University of Athens, Greece. 6. Department of Orthodontics and Dentofacial Orthopedics, Faculty of Medicine, University of Bern, Switzerland. 7. Clinic of Orthodontics and Paediatric Dentistry, Center of Dental Medicine, Faculty of Medicine, University of Zurich, Plattenstrasse 11, Zurich 8032, Switzerland. Electronic address: theodore.eliades@zzm.uzh.ch.
Abstract
OBJECTIVE: To assess the in vivo amount of BPA released from a visible light-cured orthodontic adhesive, immediately after bracket bonding. METHODS: 20 orthodontic patients were recruited after obtaining informed consent. All patients received 24 orthodontic brackets in both dental arches. In Group A (11 patients), 25 ml of tap water were used for mouth rinsing, whereas in Group B (9 patients) a simulated mouth rinse formulation was used: a mixture of 20 ml de-ionized water plus 5 ml absolute ethanol. Rinsing solutions were collected before, immediately after placing the orthodontic appliances and after washing out the oral cavity and were then stored in glass tubes. Rinsing was performed in a single phase for 60s with the entire volume of each liquid. The BPA analysis was performed by gas chromatography-mass spectrometry. RESULTS: An increase in BPA concentration immediately after the 1st post-bonding rinse was observed, for both rinsing media, which was reduced after the 2nd post-bonding rinse. Water exhibited higher levels of BPA concentration than water/ethanol after 1st and 2nd post-bonding rinses. Two-way mixed Repeated Measures ANOVA showed that the primary null hypothesis declaring mean BPA concentration to be equal across rinsing medium and rinsing status was rejected (p-value <0.001). The main effects of the rinsing medium and status, as well as their interaction were found to be statistically significant (p-values 0.048, <0.001 and 0.011 respectively). SIGNIFICANCE: A significant pattern of increase of BPA concentration, followed by a decrease that reached the initial values was observed. The amount of BPA was relatively low and far below the reference limits of tolerable daily intake.
OBJECTIVE: To assess the in vivo amount of BPA released from a visible light-cured orthodontic adhesive, immediately after bracket bonding. METHODS: 20 orthodontic patients were recruited after obtaining informed consent. All patients received 24 orthodontic brackets in both dental arches. In Group A (11 patients), 25 ml of tap water were used for mouth rinsing, whereas in Group B (9 patients) a simulated mouth rinse formulation was used: a mixture of 20 ml de-ionizedwater plus 5 ml absolute ethanol. Rinsing solutions were collected before, immediately after placing the orthodontic appliances and after washing out the oral cavity and were then stored in glass tubes. Rinsing was performed in a single phase for 60s with the entire volume of each liquid. The BPA analysis was performed by gas chromatography-mass spectrometry. RESULTS: An increase in BPA concentration immediately after the 1st post-bonding rinse was observed, for both rinsing media, which was reduced after the 2nd post-bonding rinse. Water exhibited higher levels of BPA concentration than water/ethanol after 1st and 2nd post-bonding rinses. Two-way mixed Repeated Measures ANOVA showed that the primary null hypothesis declaring mean BPA concentration to be equal across rinsing medium and rinsing status was rejected (p-value <0.001). The main effects of the rinsing medium and status, as well as their interaction were found to be statistically significant (p-values 0.048, <0.001 and 0.011 respectively). SIGNIFICANCE: A significant pattern of increase of BPA concentration, followed by a decrease that reached the initial values was observed. The amount of BPA was relatively low and far below the reference limits of tolerable daily intake.
Authors: Anabela Baptista Paula; Debbie Toste; Alfredo Marinho; Inês Amaro; Carlos-Miguel Marto; Ana Coelho; Manuel Marques-Ferreira; Eunice Carrilho Journal: Int J Environ Res Public Health Date: 2019-05-09 Impact factor: 3.390
Authors: Siemon De Nys; Eveline Putzeys; Philippe Vervliet; Adrian Covaci; Imke Boonen; Marc Elskens; Jeroen Vanoirbeek; Lode Godderis; Bart Van Meerbeek; Kirsten L Van Landuyt; Radu Corneliu Duca Journal: Sci Rep Date: 2018-05-03 Impact factor: 4.379