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Literature DB >> 26000950

Lysosomal calcium regulates autophagy.

Abstract

Recent evidence has indicated that the lysosome is able to act as a signaling organelle that senses nutrient availability and generates an adaptive response that is important for cellular homeostasis. We recently discovered another example of lysosomal signaling where lysosomal calcium release activates the master autophagy regulator TFEB via the phosphatase calcineurin.

Entities: Chemical

Keywords: TFEB; TRPML1; autophagy; calcineurin; lysosomal calcium

Mesh：

Substances：
Calcium

Year: 2015 PMID： 26000950 PMCID： PMC4502748 DOI： 10.1080/15548627.2015.1047130

Source DB: PubMed Journal: Autophagy ISSN： 1554-8627 Impact factor: 16.016

Keyword Cloud
Cited

45 in total

1. m⁶A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.

Authors: Yabing Chen; Jing Wang; Dihui Xu; Zou Xiang; Jie Ding; Xiaoyu Yang; Dongmei Li; Xiaodong Han
Journal: Autophagy Date: 2020-01-31 Impact factor: 16.016

Review 2. Calcium, mitochondrial dysfunction and slowing the progression of Parkinson's disease.

Authors: D James Surmeier; Glenda M Halliday; Tanya Simuni
Journal: Exp Neurol Date: 2017-08-02 Impact factor: 5.330

Review 3. Ion channels in the regulation of autophagy.

Authors: Artem Kondratskyi; Kateryna Kondratska; Roman Skryma; Daniel J Klionsky; Natalia Prevarskaya
Journal: Autophagy Date: 2017-11-23 Impact factor: 16.016

Review 4. Targeting autophagy in liver cancer.

Authors: Pietro Di Fazio; Sami Matrood
Journal: Transl Gastroenterol Hepatol Date: 2018-07-10

Review 5. Functional role of TRP channels in modulating ER stress and Autophagy.

Authors: Pramod Sukumaran; Anne Schaar; Yuyang Sun; Brij B Singh
Journal: Cell Calcium Date: 2016-03-11 Impact factor: 6.817

6. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis.

Authors: Nisha Singh; Pallavi Kansal; Zeeshan Ahmad; Navin Baid; Hariom Kushwaha; Neeraj Khatri; Ashwani Kumar
Journal: Autophagy Date: 2018-05-10 Impact factor: 16.016

7. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.

Authors: Paola Rusmini; Katia Cortese; Valeria Crippa; Riccardo Cristofani; Maria Elena Cicardi; Veronica Ferrari; Giulia Vezzoli; Barbara Tedesco; Marco Meroni; Elio Messi; Margherita Piccolella; Mariarita Galbiati; Massimiliano Garrè; Elena Morelli; Thomas Vaccari; Angelo Poletti
Journal: Autophagy Date: 2018-11-05 Impact factor: 16.016

Lysosomal calcium regulates autophagy.

1. m⁶A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.

Review 2. Calcium, mitochondrial dysfunction and slowing the progression of Parkinson's disease.

Review 3. Ion channels in the regulation of autophagy.

Review 4. Targeting autophagy in liver cancer.

Review 5. Functional role of TRP channels in modulating ER stress and Autophagy.

6. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis.

7. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.

Review 8. Niemann-Pick type C disease: The atypical sphingolipidosis.

9. Potassium starvation induces autophagy in yeast.

10. Acidic Ca²⁺ stores in neurodegeneration.

Lysosomal calcium regulates autophagy.

1. m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.

Review 2. Calcium, mitochondrial dysfunction and slowing the progression of Parkinson's disease.

Review 3. Ion channels in the regulation of autophagy.

Review 4. Targeting autophagy in liver cancer.

Review 5. Functional role of TRP channels in modulating ER stress and Autophagy.

6. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis.

7. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.

Review 8. Niemann-Pick type C disease: The atypical sphingolipidosis.

9. Potassium starvation induces autophagy in yeast.

10. Acidic Ca2+ stores in neurodegeneration.

1. m⁶A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.

10. Acidic Ca²⁺ stores in neurodegeneration.