Literature DB >> 26000841

Collateral DNA damage produced by genome-editing drones: exception or rule?

Andres Canela1, Andre Stanlie1, André Nussenzweig2.   

Abstract

In the recent issue of Nature Biotechnology, Frock et al. (2015) developed an elegant technique to capture translocation partners that can be utilized to determine off-target regions of genome-editing endonucleases as well as endogenous mutators at nucleotide resolution.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26000841      PMCID： PMC6289255          DOI： 10.1016/j.molcel.2015.05.012

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  10 in total

1.  Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Authors:  Isaac A Klein; Wolfgang Resch; Mila Jankovic; Thiago Oliveira; Arito Yamane; Hirotaka Nakahashi; Michela Di Virgilio; Anne Bothmer; Andre Nussenzweig; Davide F Robbiani; Rafael Casellas; Michel C Nussenzweig
Journal:  Cell       Date:  2011-09-30       Impact factor: 41.582

2.  Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes.

Authors:  Lucia Kato; Nasim A Begum; A Maxwell Burroughs; Tomomitsu Doi; Jun Kawai; Carsten O Daub; Takahisa Kawaguchi; Fumihiko Matsuda; Yoshihide Hayashizaki; Tasuku Honjo
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-30       Impact factor: 11.205

3.  Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors.

Authors:  Xiaoling Wang; Yebo Wang; Xiwei Wu; Jinhui Wang; Yingjia Wang; Zhaojun Qiu; Tammy Chang; He Huang; Ren-Jang Lin; Jiing-Kuan Yee
Journal:  Nat Biotechnol       Date:  2015-01-19       Impact factor: 54.908

Review 4.  Identification of early replicating fragile sites that contribute to genome instability.

Authors:  Jacqueline H Barlow; Robert B Faryabi; Elsa Callén; Nancy Wong; Amy Malhowski; Hua Tang Chen; Gustavo Gutierrez-Cruz; Hong-Wei Sun; Peter McKinnon; George Wright; Rafael Casellas; Davide F Robbiani; Louis Staudt; Oscar Fernandez-Capetillo; André Nussenzweig
Journal:  Cell       Date:  2013-01-24       Impact factor: 41.582

5.  Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.

Authors:  Hind Ghezraoui; Marion Piganeau; Benjamin Renouf; Jean-Baptiste Renaud; Annahita Sallmyr; Brian Ruis; Sehyun Oh; Alan E Tomkinson; Eric A Hendrickson; Carine Giovannangeli; Maria Jasin; Erika Brunet
Journal:  Mol Cell       Date:  2014-09-04       Impact factor: 17.970

6.  Spatial organization of the mouse genome and its role in recurrent chromosomal translocations.

Authors:  Yu Zhang; Rachel Patton McCord; Yu-Jui Ho; Bryan R Lajoie; Dominic G Hildebrand; Aline C Simon; Michael S Becker; Frederick W Alt; Job Dekker
Journal:  Cell       Date:  2012-02-16       Impact factor: 41.582

7.  Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.

Authors:  Roberto Chiarle; Yu Zhang; Richard L Frock; Susanna M Lewis; Benoit Molinie; Yu-Jui Ho; Darienne R Myers; Vivian W Choi; Mara Compagno; Daniel J Malkin; Donna Neuberg; Stefano Monti; Cosmas C Giallourakis; Monica Gostissa; Frederick W Alt
Journal:  Cell       Date:  2011-09-30       Impact factor: 41.582

8.  GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.

Authors:  Shengdar Q Tsai; Zongli Zheng; Nhu T Nguyen; Matthew Liebers; Ved V Topkar; Vishal Thapar; Nicolas Wyvekens; Cyd Khayter; A John Iafrate; Long P Le; Martin J Aryee; J Keith Joung
Journal:  Nat Biotechnol       Date:  2014-12-16       Impact factor: 54.908

9.  Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing.

Authors:  Nicola Crosetto; Abhishek Mitra; Maria Joao Silva; Magda Bienko; Norbert Dojer; Qi Wang; Elif Karaca; Roberto Chiarle; Magdalena Skrzypczak; Krzysztof Ginalski; Philippe Pasero; Maga Rowicka; Ivan Dikic
Journal:  Nat Methods       Date:  2013-03-17       Impact factor: 28.547

10.  Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

Authors:  Richard L Frock; Jiazhi Hu; Robin M Meyers; Yu-Jui Ho; Erina Kii; Frederick W Alt
Journal:  Nat Biotechnol       Date:  2014-12-15       Impact factor: 54.908
  10 in total
  1 in total

1.  IRF2 is a master regulator of human keratinocyte stem cell fate.

Authors:  Nicolas Mercado; Gabi Schutzius; Christian Kolter; David Estoppey; Sebastian Bergling; Guglielmo Roma; Caroline Gubser Keller; Florian Nigsch; Adrian Salathe; Remi Terranova; John Reece-Hoyes; John Alford; Carsten Russ; Judith Knehr; Dominic Hoepfner; Alexandra Aebi; Heinz Ruffner; Tanner C Beck; Sajjeev Jagannathan; Calla M Olson; Hadley E Sheppard; Selma Z Elsarrag; Tewis Bouwmeester; Mathias Frederiksen; Felix Lohmann; Charles Y Lin; Susan Kirkland
Journal:  Nat Commun       Date:  2019-10-14       Impact factor: 14.919
  1 in total

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