Literature DB >> 26000474

Deciphering the tubulin code.

Stefan Raunser1, Christos Gatsogiannis2.   

Abstract

Enzymes of the tubulin tyrosine ligase-like (TTLL) family posttranslationally modify and thereby mark microtubules by glutamylation, generating specific recognition sites for microtubule-interacting proteins. Garnham et al. report the first structure of a TTLL protein alone and in complex with microtubules, elucidating their mechanism of action.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26000474     DOI: 10.1016/j.cell.2015.05.004

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  2 in total

1.  Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.

Authors:  Yunfeng Hu; Qiu Xie; Xiang Wu; Weizhen Liu; DongFang Li; Chen Li; WangXing Zhao; LinLin Chen; Zihui Zheng; GuangMing Li; Jun Guo
Journal:  Cell Death Dis       Date:  2022-10-08       Impact factor: 9.685

2.  The carboxyl terminal mutational hotspot of the ciliary disease protein RPGRORF15 (retinitis pigmentosa GTPase regulator) is glutamylated in vivo.

Authors:  Kollu N Rao; Manisha Anand; Hemant Khanna
Journal:  Biol Open       Date:  2016-04-15       Impact factor: 2.422

  2 in total

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