Literature DB >> 25998183

Deep vein thrombosis screening and risk factors in a high-risk trauma population.

Christopher P Michetti1, Elizabeth Franco2, Jonathan Coleman2, Anna Bradford2, Amber W Trickey2.   

Abstract

BACKGROUND: Trauma patients requiring acute inpatient rehabilitation are significantly injured, with increased risk for deep vein thrombosis (DVT). We evaluated routine screening for occult DVT in such patients, and analyzed DVT risk factors.
MATERIALS AND METHODS: Data from level I trauma center patients discharged to a single acute rehabilitation center (ARC) from 2007-2011 were retrospectively reviewed. Routine lower extremity duplex was performed on ARC admission. Follow-up data were collected for patients with occult DVT (ARC DVT). DVT predictors were evaluated using logistic regression.
RESULTS: Of 622 patients, 534 (86%) had screening duplex; 26 (4.8%) had an ARC DVT. A majority of 442 patients (71%) received enoxaparin prophylaxis in hospital, for a median 64% of hospital days. Of ARC DVT patients, 17 received full anticoagulation and 16 received vena cava filters. Thirty-seven patients had DVT diagnosed in the hospital (hospital DVT) before discharge to ARC. Hospital DVT and ARC DVT groups were comparable except shorter median hospital length of stay and lower head abbreviated injury scale in ARC DVT patients. On multivariate analysis, increased intensive care unit length of stay, age >65 y, a lower percentage of hospital days receiving chemoprophylaxis, and delayed initiation of chemoprophylaxis were significantly predictive of DVT after adjustment for sex, mechanism, injury severity score, and admission systolic blood pressure. Presence of pelvic fractures and ages 50-65 y also posed an increased risk.
CONCLUSIONS: The incidence of occult DVT on ARC admission is low in trauma patients. Several risk factors for DVT in the trauma ARC population were identified. Nonselective screening of all trauma patients on admission to ARC is not supported by this analysis.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Acute rehabilitation; DVT; Enoxaparin chemoprophylaxis; Risk factors; Screening; Trauma

Mesh:

Year:  2015        PMID: 25998183     DOI: 10.1016/j.jss.2015.04.069

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  5 in total

1.  Coarse-grained molecular dynamics simulations of fibrin polymerization: effects of thrombin concentration on fibrin clot structure.

Authors:  Sumith Yesudasan; Xianqiao Wang; Rodney D Averett
Journal:  J Mol Model       Date:  2018-04-05       Impact factor: 1.810

2.  Fibrin polymerization simulation using a reactive dissipative particle dynamics method.

Authors:  Sumith Yesudasan; Xianqiao Wang; Rodney D Averett
Journal:  Biomech Model Mechanobiol       Date:  2018-05-23

3.  IQCA-TAVV: To explore the effect of P-selectin, GPIIb/IIIa, IL-2, IL-6 and IL-8 on deep venous thrombosis.

Authors:  Jianhui Wu; Haimei Zhu; Guodong Yang; Yuji Wang; Yaonan Wang; Shurui Zhao; Ming Zhao; Shiqi Peng
Journal:  Oncotarget       Date:  2017-08-24

4.  Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study.

Authors:  Qiang Li; Xiao Chen; Yuanyuan Wang; Lin Li
Journal:  Pak J Med Sci       Date:  2018 Jul-Aug       Impact factor: 1.088

5.  The risk of deep vein thrombosis in total joint patients compared to orthopaedic trauma patients: Need for new prevention guidelines.

Authors:  Michelle Shen; Norele J Cutrera; Ashley C Dodd; Christopher Wallace; Frank R Avilucea; Craig Melbourne; Alex A Jahangir; Hassan H Mir; William T Obremskey; Manish K Sethi
Journal:  J Clin Orthop Trauma       Date:  2017-01-10
  5 in total

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