Literature DB >> 25997648

Synthesis of enantioenriched 1,2-trans-diamines using the borono-Mannich reaction with N-protected α-amino aldehydes.

Stéphanie Norsikian1, Margaux Beretta, Alexandre Cannillo, Amélie Martin, Pascal Retailleau, Jean-Marie Beau.   

Abstract

The three-component Petasis borono-Mannich reaction starting with easily accessible N-protected α-amino aldehydes produces efficiently and diastereoselectively 1,2-trans-diamines with an enantiomeric excess of up to 98%.

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Year:  2015        PMID: 25997648     DOI: 10.1039/c5cc01716e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Reactivity and Synthetic Applications of Multicomponent Petasis Reactions.

Authors:  Peng Wu; Michael Givskov; Thomas E Nielsen
Journal:  Chem Rev       Date:  2019-08-27       Impact factor: 60.622

2.  Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines.

Authors:  Jimin Hwang; Lydia Borgelt; Peng Wu
Journal:  ACS Comb Sci       Date:  2020-09-28       Impact factor: 3.784

  2 in total

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