Literature DB >> 25996057

Schistosomiasis and its treatment.

Conor R Caffrey.   

Abstract

Entities:  

Keywords:  Open Source Discovery; Schistosoma; Schistosomiasis; drug development; drug resistance; medicinal chemistry; natural products; praziquantel; tropical disease

Mesh：

Substances：

Year:  2015        PMID： 25996057     DOI： 10.4155/fmc.15.27

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  29 in total

Review 1.  Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.

Authors:  Nuno Vale; Maria João Gouveia; Gabriel Rinaldi; Paul J Brindley; Fátima Gärtner; José M Correia da Costa
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

2.  A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules.

Authors:  Kimberley M Zorn; Shengxi Sun; Cecelia L McConnon; Kelley Ma; Eric K Chen; Daniel H Foil; Thomas R Lane; Lawrence J Liu; Nelly El-Sakkary; Danielle E Skinner; Sean Ekins; Conor R Caffrey
Journal:  ACS Infect Dis       Date:  2021-01-12       Impact factor: 5.084

3.  The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni.

Authors:  Betsaida Bibo-Verdugo; Steven C Wang; Jehad Almaliti; Anh P Ta; Zhenze Jiang; Derek A Wong; Christopher B Lietz; Brian M Suzuki; Nelly El-Sakkary; Vivian Hook; Guy S Salvesen; William H Gerwick; Conor R Caffrey; Anthony J O'Donoghue
Journal:  ACS Infect Dis       Date:  2019-08-12       Impact factor: 5.084

4.  The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I).

Authors:  Gustavo Salinas; Wei Gao; Yang Wang; Mariana Bonilla; Long Yu; Andrey Novikov; Veridiana G Virginio; Henrique B Ferreira; Marisol Vieites; Vadim N Gladyshev; Dinorah Gambino; Shaodong Dai
Journal:  Antioxid Redox Signal       Date:  2017-06-26       Impact factor: 8.401

5.  Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment.

Authors:  Shun Zhang; Danielle Skinner; Prateek Joshi; Ernesto Criado-Hidalgo; Yi-Ting Yeh; Juan C Lasheras; Conor R Caffrey; Juan C Del Alamo
Journal:  J R Soc Interface       Date:  2019-01-31       Impact factor: 4.118

Review 6.  The Road to Elimination: Current State of Schistosomiasis Research and Progress Towards the End Game.

Authors:  Paul Ogongo; Ruth K Nyakundi; Gerald K Chege; Lucy Ochola
Journal:  Front Immunol       Date:  2022-05-03       Impact factor: 8.786

7.  Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro.

Authors:  Ludovica Monti; Anne-Sophie Cornec; Killian Oukoloff; Jane Kovalevich; Kristen Prijs; Thibault Alle; Kurt R Brunden; Amos B Smith; Nelly El-Sakkary; Lawrence J Liu; Ali Syed; Danielle E Skinner; Carlo Ballatore; Conor R Caffrey
Journal:  ACS Infect Dis       Date:  2020-10-31       Impact factor: 5.084

8.  Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.

Authors:  Thavy Long; R Jeffrey Neitz; Rachel Beasley; Chakrapani Kalyanaraman; Brian M Suzuki; Matthew P Jacobson; Colette Dissous; James H McKerrow; David H Drewry; William J Zuercher; Rahul Singh; Conor R Caffrey
Journal:  PLoS Negl Trop Dis       Date:  2016-01-11

9.  Curcumin Generates Oxidative Stress and Induces Apoptosis in Adult Schistosoma mansoni Worms.

Authors:  Daniela de Paula Aguiar; Mayara Brunetto Moreira Moscardini; Enyara Rezende Morais; Renato Graciano de Paula; Pedro Manuel Ferreira; Ana Afonso; Silvana Belo; Amanda Tomie Ouchida; Carlos Curti; Wilson Roberto Cunha; Vanderlei Rodrigues; Lizandra Guidi Magalhães
Journal:  PLoS One       Date:  2016-11-22       Impact factor: 3.240

10.  Sex-Biased Transcriptome of Schistosoma mansoni: Host-Parasite Interaction, Genetic Determinants and Epigenetic Regulators Are Associated with Sexual Differentiation.

Authors:  Marion A L Picard; Jérôme Boissier; David Roquis; Christoph Grunau; Jean-François Allienne; David Duval; Eve Toulza; Nathalie Arancibia; Conor R Caffrey; Thavy Long; Sabine Nidelet; Marine Rohmer; Céline Cosseau
Journal:  PLoS Negl Trop Dis       Date:  2016-09-27
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