Literature DB >> 2599471

Conservative surgical management of superficially invasive stage I vulvar carcinoma.

M L Berman1, J T Soper, W T Creasman, G T Olt, P J DiSaia.   

Abstract

Fifty patients with stage I squamous cell carcinoma of the vulva were treated by means of wide local excision and either unilateral or bilateral superficial inguinal lymphadenectomy. Depth of invasion per se was not an exclusionary criterion; however, 36 of 37 patients for whom depth of invasion could be assessed had tumors invasive to a maximum depth of 5 mm. Factors investigated included recurrences and survival in addition to the early and delayed morbidity associated with this operative approach. Recurrent intraepithelial or minimally invasive cancer was documented in six patients, five of whom were treated successfully by a subsequent wide local excision following initial surgery. Only one patient died of recurrent carcinoma 16 months following surgery. The morbidity with this operation was appreciably less than that generally reported with more extensive operations commonly employed in the management of vulvar cancer and is recommended for management of patients with early invasive disease.

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Mesh:

Year:  1989        PMID: 2599471     DOI: 10.1016/0090-8258(89)90078-4

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  6 in total

1.  Lymphatic mapping and sentinel lymph node biopsy in women with squamous cell carcinoma of the vulva: a gynecologic oncology group study.

Authors:  Charles F Levenback; Shamshad Ali; Robert L Coleman; Michael A Gold; Jeffrey M Fowler; Patricia L Judson; Maria C Bell; Koen De Geest; Nick M Spirtos; Ronald K Potkul; Mario M Leitao; Jamie N Bakkum-Gamez; Emma C Rossi; Samuel S Lentz; James J Burke; Linda Van Le; Cornelia L Trimble
Journal:  J Clin Oncol       Date:  2012-07-02       Impact factor: 44.544

2.  Is bilateral lymphadenectomy for midline squamous carcinoma of the vulva always necessary? An analysis from Gynecologic Oncology Group (GOG) 173.

Authors:  Robert L Coleman; Shamshad Ali; Charles F Levenback; Michael A Gold; Jeffrey M Fowler; Patricia L Judson; Maria C Bell; Koen De Geest; Nick M Spirtos; Ronald K Potkul; Mario M Leitao; Jamie N Bakkum-Gamez; Emma C Rossi; Samuel S Lentz; James J Burke; Linda Van Le; Cornelia L Trimble
Journal:  Gynecol Oncol       Date:  2012-11-29       Impact factor: 5.482

Review 3.  Vulvar carcinoma.

Authors:  R L Coleman; J T Santoso
Journal:  Curr Treat Options Oncol       Date:  2000-06

4.  Selective inguinal lymphadenectomy in the treatment of invasive squamous cell carcinoma of the vulva.

Authors:  Christopher P Desimone; Jeffrey Elder; John R van Nagell
Journal:  Int J Surg Oncol       Date:  2011-06-09

Review 5.  Emotional and sexual concerns in women undergoing pelvic surgery and associated treatment for gynecologic cancer.

Authors:  Cara Stabile; Abigail Gunn; Yukio Sonoda; Jeanne Carter
Journal:  Transl Androl Urol       Date:  2015-04

6.  Japan Society of Gynecologic Oncology guidelines 2015 for the treatment of vulvar cancer and vaginal cancer.

Authors:  Toshiaki Saito; Tsutomu Tabata; Hitoshi Ikushima; Hiroyuki Yanai; Hironori Tashiro; Hitoshi Niikura; Takeo Minaguchi; Toshinari Muramatsu; Tsukasa Baba; Wataru Yamagami; Kazuya Ariyoshi; Kimio Ushijima; Mikio Mikami; Satoru Nagase; Masanori Kaneuchi; Nobuo Yaegashi; Yasuhiro Udagawa; Hidetaka Katabuchi
Journal:  Int J Clin Oncol       Date:  2017-11-20       Impact factor: 3.402

  6 in total

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