Biological activity of natural sesquiterpenoids containing a gem-dimethylcyclopropane unit.

The biological activities of aristolane, aromadendrane, ent-1,10-secoaromadendrane, 2,3-secoaromadendrane, ent-5,10-cycloaromadendrane, bicyclogermacrene, lepidozane, and maaliane terpenoids which contain the gem-dimethylcyclopropyl unit are described. Particular attention is given to their anti-viral, anti-microbial and cytotoxic activities. In the main text there are 119 references covering the literature from 1963-2014. The ESI contains tables listing 332 of these terpenoids, their occurrence and biological activity together with the related references.