Literature DB >> 25992850

IL-2: Change Structure … Change Function.

Jeffrey A Bluestone1, Natasha Crellin2, Eleonora Trotta3.   

Abstract

In this issue of Immunity, Spangler et al. and Mitra et al. demonstrate how structural changes in the IL-2 molecule alter interactions with the IL-2 receptor, leading to differential cellular targeting and biochemical responses and selective immune consequences.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 25992850     DOI: 10.1016/j.immuni.2015.05.002

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  5 in total

Review 1.  Harnessing the plasticity of CD4(+) T cells to treat immune-mediated disease.

Authors:  Michel DuPage; Jeffrey A Bluestone
Journal:  Nat Rev Immunol       Date:  2016-02-15       Impact factor: 53.106

2.  Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators.

Authors:  Colin R Zamecnik; Margaret M Lowe; David M Patterson; Michael D Rosenblum; Tejal A Desai
Journal:  ACS Nano       Date:  2017-11-15       Impact factor: 15.881

Review 3.  Academic, Foundation, and Industry Collaboration in Finding New Therapies.

Authors:  Bonnie W Ramsey; Gerald T Nepom; Sagar Lonial
Journal:  N Engl J Med       Date:  2017-05-04       Impact factor: 91.245

Review 4.  Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy.

Authors:  Jing Gao; Wei-Qi Wang; Qing Pei; Megan S Lord; Hai-Jun Yu
Journal:  Acta Pharmacol Sin       Date:  2020-04-21       Impact factor: 6.150

5.  Characterization of bovine interleukin-2 stably expressed in HEK-293 cells.

Authors:  Shuya Mitoma; Heba M El-Khaiat; Tomofumi Uto; Katsuaki Sato; Satoshi Sekiguchi; Junzo Norimine
Journal:  J Vet Med Sci       Date:  2020-11-11       Impact factor: 1.267

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.