Literature DB >> 25992694

Assesment of the treatment of earlobe keloids with triamcinolone injections, surgical resection, and local pressure.

Silvia Mandello Carvalhaes1, Andy Petroianu2, Mauro Augusto Tostes Ferreira3, Virgínea Magalhães de Barros4, Raquel Virgínea Lopes4.   

Abstract

OBJECTIVE: To evaluate the combined treatment of ear lobe keloids.
METHODS: We studied 46 consecutive patients with 81 ear lobe keloids. Patients underwent local infiltration of triamcinolone acetonide (TCN) at concentrations of 40 mg/ml (Group 1), 20 mg/ml (Group 2) and 10mg/ml (Group 3). The volume of TCN infiltrate varied according to the size of the lesion. Treatment consisted of three monthly injections before surgery, excision of keloid in the fourth month and perioperative infiltration, followed by two more leaks TCN within two months. Patients used earrings pressure on the scar after operation for four months. The pressure exerted by earrings in the ear lobe was measured electronically. Post-treatment follow-up of patients was 24 months.
RESULTS: TCN at concentrations of 20mg/ml and 40 mg/ml were effective for the treatment of keloids, no difference between the groups (p = 0.58). However, patients in which TCN was infiltrated the 10mg/ml had poor involution of keloid and the study of this group was stopped.
CONCLUSION: the combination of infiltration TCN month to 20 mg/mL (1.2mg to 2.0mg per mm3 TCN injury), surgical excision and pressure application device is effective for treatment of keloid ear lobe.

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Year:  2015        PMID: 25992694     DOI: 10.1590/0100-69912015001003

Source DB:  PubMed          Journal:  Rev Col Bras Cir        ISSN: 0100-6991


  6 in total

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Review 4.  Triamcinolone acetonide intralesional injection for the treatment of keloid scars: patient selection and perspectives.

Authors:  Marco Morelli Coppola; Rosa Salzillo; Francesco Segreto; Paolo Persichetti
Journal:  Clin Cosmet Investig Dermatol       Date:  2018-07-24

5.  Management of Ear Keloids Using Surgical Excision Combined with Postoperative Steroid Injections.

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6.  Effect of UVA1 on hypertrophic scarring in the rabbit ear model.

Authors:  Tong Zhang; Zhiming Shen; Jie Zheng; Rui Jiang
Journal:  Biosci Rep       Date:  2020-01-31       Impact factor: 3.840

  6 in total

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