Electrophysiological effects of fenfluramine or combined vitamin B6 and magnesium on children with autistic behaviour.

The authors compared the effects of fenfluramine or combined vitamin B6 and magnesium treatment on the evoked potential conditioning of 12 children whose autistic behaviour had improved clinically following treatment. The children who were clinically sensitive to combined vitamin B6 and magnesium developed a conditioning phenomenon and the fenfluramine-sensitive children showed an enhancement of the Cz evoked response amplitude. Results are discussed with reference to behaviour modifications observed during treatment.