Literature DB >> 25992375

A specific molecular signature for psoriasis and eczema.

Susana Coimbra1, Alice Santos-Silva1.   

Abstract

Psoriasis and eczema seem to present a specific distinctive gene expression pattern. In the Science Translation Medicine (Sci Transl Med), Quaranta et al. reported a specific molecular signature of psoriasis and eczema. By using an intraindividual genome expression analysis in patients affected by both diseases, the authors identified genes and signaling pathways that are regulated in common and that are exclusive for each disease.

Entities:  

Keywords:  CCL27 gene; NOS2 gene; Psoriasis; disease classifier; eczema; gene expression

Year:  2015        PMID： 25992375      PMCID： PMC4416959          DOI： 10.3978/j.issn.2305-5839.2015.01.24

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN： 2305-5839


  20 in total

1.  Kinetics and differential expression of the skin-related chemokines CCL27 and CCL17 in psoriasis, atopic dermatitis and allergic contact dermatitis.

Authors:  Jette L Riis; Claus Johansen; Christian Vestergaard; Rikke Bech; Knud Kragballe; Lars Iversen
Journal:  Exp Dermatol       Date:  2011-06-24       Impact factor: 3.960

Review 2.  Contrasting pathogenesis of atopic dermatitis and psoriasis--part II: immune cell subsets and therapeutic concepts.

Authors:  Emma Guttman-Yassky; Kristine E Nograles; James G Krueger
Journal:  J Allergy Clin Immunol       Date:  2011-03-21       Impact factor: 10.793

3.  Interleukin (IL)-22, IL-17, IL-23, IL-8, vascular endothelial growth factor and tumour necrosis factor-α levels in patients with psoriasis before, during and after psoralen-ultraviolet A and narrowband ultraviolet B therapy.

Authors:  S Coimbra; H Oliveira; F Reis; L Belo; S Rocha; A Quintanilha; A Figueiredo; F Teixeira; E Castro; P Rocha-Pereira; A Santos-Silva
Journal:  Br J Dermatol       Date:  2010-11-08       Impact factor: 9.302

4.  A milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis.

Authors:  Cristina de Guzman Strong; Sean Conlan; Clayton B Deming; Jun Cheng; Karen E Sears; Julia A Segre
Journal:  Hum Mol Genet       Date:  2010-01-20       Impact factor: 6.150

5.  Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.

Authors:  Emma Guttman-Yassky; Michelle A Lowes; Judilyn Fuentes-Duculan; Lisa C Zaba; Irma Cardinale; Kristine E Nograles; Artemis Khatcherian; Inna Novitskaya; John A Carucci; Reuven Bergman; James G Krueger
Journal:  J Immunol       Date:  2008-11-15       Impact factor: 5.422

6.  Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis.

Authors:  Ichiro Nomura; Bifeng Gao; Mark Boguniewicz; Marc A Darst; Jeffrey B Travers; Donald Y m Leung
Journal:  J Allergy Clin Immunol       Date:  2003-12       Impact factor: 10.793

7.  Psoriasis genomics: analysis of proinflammatory (type 1) gene expression in large plaque (Western) and small plaque (Asian) psoriasis vulgaris.

Authors:  W Lew; E Lee; J G Krueger
Journal:  Br J Dermatol       Date:  2004-04       Impact factor: 9.302

8.  IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.

Authors:  Kristine E Nograles; Lisa C Zaba; Avner Shemer; Judilyn Fuentes-Duculan; Irma Cardinale; Toyoko Kikuchi; Michal Ramon; Reuven Bergman; James G Krueger; Emma Guttman-Yassky
Journal:  J Allergy Clin Immunol       Date:  2009-05-12       Impact factor: 10.793

Review 9.  An update on the genetics of atopic dermatitis: scratching the surface in 2009.

Authors:  Kathleen C Barnes
Journal:  J Allergy Clin Immunol       Date:  2010-01       Impact factor: 10.793

10.  Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect.

Authors:  Sara J Brown; Karin Kroboth; Aileen Sandilands; Linda E Campbell; Elizabeth Pohler; Sanja Kezic; Heather J Cordell; W H Irwin McLean; Alan D Irvine
Journal:  J Invest Dermatol       Date:  2011-11-10       Impact factor: 8.551
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  1 in total

Review 1.  The immunogenetics of Psoriasis: A comprehensive review.

Authors:  Jamie L Harden; James G Krueger; Anne M Bowcock
Journal:  J Autoimmun       Date:  2015-07-26       Impact factor: 7.094
  1 in total

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