| Literature DB >> 2598995 |
P Kintz1, P Mangin, A A Lugnier, A J Chaumont.
Abstract
A capillary gas chromatography mass spectrometry assay has been developed for the determination of 6-monoacetylmorphine in human urine, which is a confirmatory marker of heroin abuse. It was extracted with chloroform-isopropanol-n-heptane (50:17:33, v/v) from alkalinized samples (pH 9.2), using levallorphan as the internal standard. After derivatization with trifluoroacetic anhydride, the drugs were separated on a 25-m capillary column BP 10 and detected by selected ion monitoring.Entities:
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Year: 1989 PMID： 2598995 DOI： 10.1007/bf00558138
Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953