| Literature DB >> 25987307 |
Frederico O Gleber-Netto1, Boudewijn J M Braakhuis2, Asterios Triantafyllou3, Robert P Takes4, Natalie Kelner5, Juan P Rodrigo6, Primož Strojan7, Vincent Vander Poorten8, Alexander D Rapidis9, Alessandra Rinaldo10, Ruud H Brakenhoff2, Alfio Ferlito11, Luiz P Kowalski12.
Abstract
Relapses have a great impact on both the morbidity and mortality rates of oral squamous cell carcinoma (OSCC) patients. Current classification criteria are imprecise and need improvements. Recent advances in understanding of OSCC relapses on a molecular level provide new possibilities to better classify true recurrences and second primary tumors. This review discusses the limitations of the current OSCC relapse classification method and presents possible alternatives to improve this classification based on molecular techniques. Moreover, these molecular techniques add to the further understanding of these lesions and may provide tools for clinical management.Entities:
Keywords: Molecular diagnosis; Oral cancer; Recurrence; Relapse; Second primary neoplasm; Squamous cell carcinoma
Mesh：
Year: 2015 PMID： 25987307 DOI： 10.1016/j.oraloncology.2015.04.016
Source DB: PubMed Journal: Oral Oncol ISSN： 1368-8375 Impact factor: 5.337