Kathleen M Miller1, Emma Chad-Friedman2, Vivian Haime3, Darshan H Mehta4, Veronique Lepoutre5, Dinah Gilburd6, Donna Peltier-Saxe7, Cally Lilley8, Herbert Benson9, Gregory L Fricchione10, John W Denninger11, Albert Yeung12. 1. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Dr Miller), United States. 2. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Ms Chad-Friedman), United States. 3. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Ms Haime), United States. 4. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Dr Mehta), United States. 5. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Ms Lepoutre), United States. 6. MGH Charlestown Health Center (Ms Gilburd), United States. 7. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Ms Peltier-Saxe), United States. 8. Red Sox Foundation, Boston, and MGH Home Base Program (Ms Lilley), United States. 9. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Dr Benson), United States. 10. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Dr Fricchione), United States. 11. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Dr Denninger), United States. 12. Benson-Henry Institute for Mind Body Medicine at the Massachusetts General Hospital (MGH), Boston (Dr Yeung), United States.
Abstract
OBJECTIVE: The objective of this pilot study was to examine the effects of a brief, 6-week, 1.5-hour mind-body intervention for depression (MBID) in patients being treated for depression in 2 community health centers. DESIGN: The MBID taught techniques such as meditation that elicit the relaxation response (RR) in combination with additional resiliency-enhancing components. Clinical outcomes of 24 depressed patients were measured pre-MBID, at completion of MBID, and 3 months post-MBID, using the Center for Epidemiological Studies Depression Scale (CES-D 10), Quality of Life Scale (QoL5), SF-12 Health Survey (SF-12), and Health-Promoting Lifestyle Profile-II (HPLP-II). RESULTS: Significant post-treatment improvements were shown in depressive symptoms, spiritual growth, mental health, and quality of life, with a median CES-D 10 change from 17.5 (interquartile ratio [IQR] 13.3-22) to 12 (IQR 10-17.5; P<.001); a median HPLP-II Spiritual Growth subscale change from 2.0 (IQR 1.8-2.3) to 2.3 (IQR 2.0-3.0; P=.002) and a median HPLP-II Stress Management subscale change from 2.0 (IQR 1.8-2.4) to 2.4 (IQR 2.0-2.9; P=.027); significant improvement in median score on the QoL-5 from 53.3 (IQR 47.5-62.5) at baseline to 63.3 at endpoint (IQR 50-70; P=.008). Three-month follow-up data suggest that the improvement in outcomes were sustained 3 months after the intervention. CONCLUSIONS: Participation in a 6-week RR-based MBID is associated with an improvement in depression, spiritual growth, and mental health among depressed community health center patients.
OBJECTIVE: The objective of this pilot study was to examine the effects of a brief, 6-week, 1.5-hour mind-body intervention for depression (MBID) in patients being treated for depression in 2 community health centers. DESIGN: The MBID taught techniques such as meditation that elicit the relaxation response (RR) in combination with additional resiliency-enhancing components. Clinical outcomes of 24 depressedpatients were measured pre-MBID, at completion of MBID, and 3 months post-MBID, using the Center for Epidemiological Studies Depression Scale (CES-D 10), Quality of Life Scale (QoL5), SF-12 Health Survey (SF-12), and Health-Promoting Lifestyle Profile-II (HPLP-II). RESULTS: Significant post-treatment improvements were shown in depressive symptoms, spiritual growth, mental health, and quality of life, with a median CES-D 10 change from 17.5 (interquartile ratio [IQR] 13.3-22) to 12 (IQR 10-17.5; P<.001); a median HPLP-II Spiritual Growth subscale change from 2.0 (IQR 1.8-2.3) to 2.3 (IQR 2.0-3.0; P=.002) and a median HPLP-II Stress Management subscale change from 2.0 (IQR 1.8-2.4) to 2.4 (IQR 2.0-2.9; P=.027); significant improvement in median score on the QoL-5 from 53.3 (IQR 47.5-62.5) at baseline to 63.3 at endpoint (IQR 50-70; P=.008). Three-month follow-up data suggest that the improvement in outcomes were sustained 3 months after the intervention. CONCLUSIONS: Participation in a 6-week RR-based MBID is associated with an improvement in depression, spiritual growth, and mental health among depressed community health center patients.
Entities:
Keywords:
Mind-body; community health centers; depression; relaxation response
Authors: Birgitte Boye; Knut E A Lundin; Günter Jantschek; Siv Leganger; Kjell Mokleby; Tone Tangen; Ingrid Jantschek; Are H Pripp; Swavek Wojniusz; Astri Dahlstroem; Ann Christin Rivenes; Dieter Benninghoven; Trygve Hausken; Arne Roseth; Sebastian Kunzendorf; Ingvard Wilhelmsen; Michael Sharpe; Svein Blomhoff; Ulrik F Malt; Jorgen Jahnsen Journal: Inflamm Bowel Dis Date: 2011-02-01 Impact factor: 5.325
Authors: B Gandek; J E Ware; N K Aaronson; G Apolone; J B Bjorner; J E Brazier; M Bullinger; S Kaasa; A Leplege; L Prieto; M Sullivan Journal: J Clin Epidemiol Date: 1998-11 Impact factor: 6.437