Literature DB >> 25983828

Primary malignant lymphoma in a spinal cord presenting as an epidural mass with myelopathy: a case report.

Jae-Hoon Cho1, Dae-Chul Cho1, Joo-Kyung Sung1, Kyoung-Tae Kim1.   

Abstract

We report the case of a 47-year-old man who presented with progressive paraparesis and sphincter changes over 2 weeks. Magnetic resonance imaging revealed a spinal epidural mass from T9 to L2. We performed a decompressive laminectomy and mass removal. The histopathology was consistent with a small lymphocytic lymphoma. No metastatic lesion was noted in the chest and abdomen-pelvic computerized tomography (CT) and positron emission tomography computerized tomography (PET-CT) scan. The final diagnosis was primary spinal lymphoma, so we performed chemotherapy combined with radiotherapy. At one year follow-up, he had no neurological deficit and no recurrence on neurologic and radiologic exams. Primary spinal cord lymphomas should be considered in the differential diagnosis of spinal cord tumors. Early surgical management is mandatory to achieve a recovery of neurologic function, especially if the patient has a neurological deficit.

Entities:  

Keywords:  Chemo-radiotherapy; Decompressive laminectomy; Primary Spinal Lymphoma; Spinal Epidural Mass

Year:  2012        PMID: 25983828      PMCID: PMC4431015          DOI: 10.14245/kjs.2012.9.3.265

Source DB:  PubMed          Journal:  Korean J Spine        ISSN: 1738-2262


  20 in total

Review 1.  Isolated primary non-Hodgkin's lymphoma of the thoracic spine: a case report with a review of the literature.

Authors:  J S Zheng; M Wang; S Wan; Y Q Zhou; M Yan; Q F Chen; R Y Zhan
Journal:  J Int Med Res       Date:  2010 Jul-Aug       Impact factor: 1.671

2.  Primary vertebral and spinal epidural non-Hodgkin's lymphoma with spinal cord compression.

Authors:  M Boukobza; C Mazel; E Touboul
Journal:  Neuroradiology       Date:  1996-05       Impact factor: 2.804

3.  Lymphoma of the spinal extradural space.

Authors:  P Haddad; J F Thaell; J M Kiely; E G Harrison; R H Miller
Journal:  Cancer       Date:  1976-10       Impact factor: 6.860

4.  Lymphomas: MR imaging contrast characteristics with clinical-pathologic correlations.

Authors:  W G Negendank; A M al-Katib; C Karanes; M R Smith
Journal:  Radiology       Date:  1990-10       Impact factor: 11.105

5.  Primary non-Hodgkin's lymphoma in multiple vertebrae presenting as a lumbar radicular syndrome: A case report.

Authors:  S C M Ebus; H J J A Bernsen; G J Norel Van; R Donk
Journal:  Spine (Phila Pa 1976)       Date:  2002-05-15       Impact factor: 3.468

6.  MR imaging of spinal lymphoma.

Authors:  M H Li; S Holtås; E M Larsson
Journal:  Acta Radiol       Date:  1992-07       Impact factor: 1.990

7.  Primary spinal epidural mantle cell lymphoma: case report.

Authors:  M Barnard; B Perez-Ordoñez; D W Rowed; L C Ang
Journal:  Neurosurgery       Date:  2000-11       Impact factor: 4.654

8.  Primary spinal epidural lymphoma: patients' profile, outcome, and prognostic factors: a multicenter Rare Cancer Network study.

Authors:  Virginie Monnard; Alex Sun; Ron Epelbaum; Philip Poortmans; Robert C Miller; Tom Verschueren; Luciano Scandolaro; Salvador Villa; Sabine Balmer Majno; Sandrine Ostermann; Mahmut Ozsahin; René-Olivier Mirimanoff
Journal:  Int J Radiat Oncol Biol Phys       Date:  2006-03-15       Impact factor: 7.038

9.  Acute lymphocytic leukemia recurring in the spinal epidural space.

Authors:  Tetsuhiro Higashida; Takashi Kawasaki; Katsumi Sakata; Yutaka Tanabe; Hiroshi Kanno; Isao Yamamoto
Journal:  Neurol Med Chir (Tokyo)       Date:  2007-08       Impact factor: 1.742

10.  Isolated, primary spinal epidural Hodgkin's disease in a child.

Authors:  Mohammad Samadian; Shifteh Vahidi; Fatemeh Khormaee; Haleh Ashraf
Journal:  Pediatr Neurol       Date:  2009-06       Impact factor: 3.372

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  2 in total

1.  A Rare Case of Malignant Lymphoma Occurred at Spinal Epidural Space: A Case Report.

Authors:  Hyun-Jun Cho; Jang-Bo Lee; Junseok W Hur; Sung-Won Jin; Tai-Hyoung Cho; Jung-Yul Park
Journal:  Korean J Spine       Date:  2015-09-30

2.  Diffuse Large B-Cell Lymphoma Mimicking Schwannoma of Lumbar Spine.

Authors:  Seung-Kook Kim; Sun-Ho Lee; Eun-Sang Kim; Whan Eoh
Journal:  Korean J Spine       Date:  2016-06-30
  2 in total

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