Bizu Gelaye1, Yasmin V Barrios2, Qiu-Yue Zhong2, Marta B Rondon3, Christina P C Borba4, Sixto E Sánchez5, David C Henderson6, Michelle A Williams2. 1. Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA. Electronic address: bgelaye@hsph.harvard.edu. 2. Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA. 3. Department of Medicine, Cayetano Heredia Peruvian University, Lima, Peru. 4. Harvard Medical School, Boston, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA. 5. Universidad Peruana de Ciencias Aplicadas, Lima, Peru; Asociación Civil PROESA, Lima, Peru. 6. Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Abstract
OBJECTIVE: To examine the independent and joint relationships of poor subjective sleep quality and antepartum depression with suicidal ideation among pregnant women. METHODS: A cross-sectional study was conducted among 641 pregnant women attending prenatal care clinics in Lima, Peru. Antepartum depression and suicidal ideation were assessed using the Patient Health Questionnaire-9 scale. Antepartum subjective sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Logistic regression procedures were performed to estimate odds ratios (aOR) and 95% confidence intervals (95% CI) adjusted for confounders. RESULTS: Overall, the prevalence of suicidal ideation in this cohort was 16.8% and poor subjective sleep quality was more common among women endorsing suicidal ideation as compared to their counterparts who did not (47.2% vs. 24.8%, P<.001). After adjustment for confounders including maternal depression, poor subjective sleep quality (defined using the recommended criteria of PSQI global score of >5 vs. ≤5) was associated with a 1.7-fold increased odds of suicidal ideation (aOR=1.67; 95% CI 1.02-2.71). When assessed as a continuous variable, each 1-unit increase in the global PSQI score resulted in an 18% increase in odds for suicidal ideation, even after adjusting for depression (aOR=1.18; 95% CI 1.08-1.28). Women with both poor subjective sleep quality and depression had a 3.5-fold increased odds of suicidal ideation (aOR=3.48; 95% CI 1.96-6.18) as compared with those who had neither risk factor. CONCLUSION: Poor subjective sleep quality was associated with increased odds of suicidal ideation. Replication of these findings may promote investments in studies designed to examine the efficacy of sleep-focused interventions to treat pregnant women with sleep disorders and suicidal ideation.
OBJECTIVE: To examine the independent and joint relationships of poor subjective sleep quality and antepartum depression with suicidal ideation among pregnant women. METHODS: A cross-sectional study was conducted among 641 pregnant women attending prenatal care clinics in Lima, Peru. Antepartum depression and suicidal ideation were assessed using the Patient Health Questionnaire-9 scale. Antepartum subjective sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Logistic regression procedures were performed to estimate odds ratios (aOR) and 95% confidence intervals (95% CI) adjusted for confounders. RESULTS: Overall, the prevalence of suicidal ideation in this cohort was 16.8% and poor subjective sleep quality was more common among women endorsing suicidal ideation as compared to their counterparts who did not (47.2% vs. 24.8%, P<.001). After adjustment for confounders including maternal depression, poor subjective sleep quality (defined using the recommended criteria of PSQI global score of >5 vs. ≤5) was associated with a 1.7-fold increased odds of suicidal ideation (aOR=1.67; 95% CI 1.02-2.71). When assessed as a continuous variable, each 1-unit increase in the global PSQI score resulted in an 18% increase in odds for suicidal ideation, even after adjusting for depression (aOR=1.18; 95% CI 1.08-1.28). Women with both poor subjective sleep quality and depression had a 3.5-fold increased odds of suicidal ideation (aOR=3.48; 95% CI 1.96-6.18) as compared with those who had neither risk factor. CONCLUSION: Poor subjective sleep quality was associated with increased odds of suicidal ideation. Replication of these findings may promote investments in studies designed to examine the efficacy of sleep-focused interventions to treat pregnant women with sleep disorders and suicidal ideation.
Authors: Viktor Roman; Karin Van der Borght; Susan A Leemburg; Eddy A Van der Zee; Peter Meerlo Journal: Brain Res Date: 2005-11-23 Impact factor: 3.252
Authors: Carolyn L Turvey; Yeates Conwell; Michael P Jones; Caroline Phillips; Eleanor Simonsick; Jane L Pearson; Robert Wallace Journal: Am J Geriatr Psychiatry Date: 2002 Jul-Aug Impact factor: 4.105
Authors: Abigail M Pauley; Ginger A Moore; Scherezade K Mama; Peter Molenaar; Danielle Symons Downs Journal: J Clin Sleep Med Date: 2020-04-15 Impact factor: 4.062
Authors: Qiu-Yue Zhong; Anne Wells; Marta B Rondon; Michelle A Williams; Yasmin V Barrios; Sixto E Sanchez; Bizu Gelaye Journal: Am J Obstet Gynecol Date: 2016-05-10 Impact factor: 8.661
Authors: Lauren E Friedman; Bizu Gelaye; Marta B Rondon; Sixto E Sanchez; B Lee Peterlin; Michelle A Williams Journal: Headache Date: 2016-03-26 Impact factor: 5.887
Authors: Elia Rubio; Elizabeth J Levey; Marta B Rondon; Lauren Friedman; Sixto E Sanchez; Michelle A Williams; Bizu Gelaye Journal: Matern Child Health J Date: 2022-05-21
Authors: L Ongeri; C E McCulloch; T C Neylan; E Bukusi; S B Macfarlane; C Othieno; A K Ngugi; S M Meffert Journal: J Affect Disord Date: 2017-08-31 Impact factor: 4.839
Authors: Chunfang Qiu; Bizu Gelaye; Qiu-Yue Zhong; Daniel A Enquobahrie; Ihunnaya O Frederick; Michelle A Williams Journal: Sleep Breath Date: 2016-01-25 Impact factor: 2.816
Authors: David A Kalmbach; Philip Cheng; Jason C Ong; Jeffrey A Ciesla; Sheryl A Kingsberg; Roopina Sangha; Leslie M Swanson; Louise M O'Brien; Thomas Roth; Christopher L Drake Journal: Sleep Med Date: 2019-07-22 Impact factor: 3.492