Literature DB >> 25979767

The role of purinergic signalling in the musculoskeletal system.

Isabel R Orriss1.   

Abstract

Accumulating evidence now suggests that purinergic signalling exerts significant regulatory effects in the musculoskeletal system. In particular, it has emerged that extracellular nucleotides are key regulators of bone cell differentiation, survival and function. This review discusses our current understanding of the direct effects of purinergic signalling in bone, cartilage and muscle.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  ATP; Bone; Cartilage; Mineralisation; Muscle; P2 receptors

Mesh：

Substances：

Year:  2015        PMID： 25979767     DOI： 10.1016/j.autneu.2015.04.013

Source DB:  PubMed          Journal:  Auton Neurosci        ISSN： 1566-0702            Impact factor:   3.145


  8 in total

1.  Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.

Authors:  Kristina Palmer; Heather Fairfield; Suhaib Borgeia; Michelle Curtain; Mohamed G Hassan; Louise Dionne; Son Yong Karst; Harold Coombs; Roderick T Bronson; Laura G Reinholdt; David E Bergstrom; Leah Rae Donahue; Timothy C Cox; Stephen A Murray
Journal:  Dev Biol       Date:  2015-07-31       Impact factor: 3.582

2.  Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms.

Authors:  Jessal J Patel; Dongxing Zhu; Britt Opdebeeck; Patrick D'Haese; José L Millán; Lucie E Bourne; Caroline P D Wheeler-Jones; Timothy R Arnett; Vicky E MacRae; Isabel R Orriss
Journal:  J Cell Physiol       Date:  2017-10-04       Impact factor: 6.384

3.  Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation.

Authors:  Isabel R Orriss; Timothy R Arnett; Jacob George; Miles D Witham
Journal:  Exp Cell Res       Date:  2016-03-08       Impact factor: 3.905

Review 4.  Small Molecules Enhance Scaffold-Based Bone Grafts via Purinergic Receptor Signaling in Stem Cells.

Authors:  Patrick Frank Ottensmeyer; Markus Witzler; Margit Schulze; Edda Tobiasch
Journal:  Int J Mol Sci       Date:  2018-11-14       Impact factor: 5.923

5.  The Adenosine A2B Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments.

Authors:  Helen J Knowles
Journal:  Cells       Date:  2019-06-21       Impact factor: 6.600

Review 6.  Extracellular Nucleotides Regulate Arterial Calcification by Activating Both Independent and Dependent Purinergic Receptor Signaling Pathways.

Authors:  Britt Opdebeeck; Isabel R Orriss; Ellen Neven; Patrick C D'Haese; Anja Verhulst
Journal:  Int J Mol Sci       Date:  2020-10-15       Impact factor: 5.923

7.  Mechanical Disturbance of Osteoclasts Induces ATP Release That Leads to Protein Synthesis in Skeletal Muscle through an Akt-mTOR Signaling Pathway.

Authors:  Camilo Morales-Jiménez; Julián Balanta-Melo; Manuel Arias-Calderón; Nadia Hernández; Fernán Gómez-Valenzuela; Alejandro Escobar; Enrique Jaimovich; Sonja Buvinic
Journal:  Int J Mol Sci       Date:  2022-08-21       Impact factor: 6.208

8.  Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways.

Authors:  Maria Prendecki; Stephen P McAdoo; Tabitha Turner-Stokes; Ana Garcia-Diaz; Isabel Orriss; Kevin J Woollard; Jacques Behmoaras; H Terence Cook; Robert Unwin; Charles D Pusey; Timothy J Aitman; Frederick Wk Tam
Journal:  J Pathol       Date:  2022-05-02       Impact factor: 9.883
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.