Literature DB >> 25979482

Stroma, Stroma Everywhere (Far More Than You Think).

Kenneth P Olive1.   

Abstract

Pancreatic ductal adenocarcinomas with high stromal content are shown to have greatly reduced overall survival, consistent with previous reports that stroma may limit drug delivery. In contrast to expectations, metastatic lesions were found to harbor as much stroma as primary tumors. ©2015 American Association for Cancer Research.

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Year:  2015        PMID: 25979482     DOI: 10.1158/1078-0432.CCR-15-0416

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  6 in total

1.  Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.

Authors:  Daoxiang Zhang; Lin Li; Hongmei Jiang; Qiong Li; Andrea Wang-Gillam; Jinsheng Yu; Richard Head; Jingxia Liu; Marianna B Ruzinova; Kian-Huat Lim
Journal:  Cancer Res       Date:  2018-01-23       Impact factor: 12.701

2.  Pragmatic medicine in solid cancer: a translational alternative to precision medicine.

Authors:  Jan Brábek; Daniel Rosel; Michael Fernandes
Journal:  Onco Targets Ther       Date:  2016-04-05       Impact factor: 4.147

Review 3.  Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward.

Authors:  Mohammad Aslam Aslam Khan; Shafquat Azim; Haseeb Zubair; Arun Bhardwaj; Girijesh Kumar Patel; Moh'd Khushman; Seema Singh; Ajay Pratap Singh
Journal:  Int J Mol Sci       Date:  2017-04-06       Impact factor: 5.923

Review 4.  Potential Therapeutic Applications of N-Cadherin Antagonists and Agonists.

Authors:  Orest W Blaschuk
Journal:  Front Cell Dev Biol       Date:  2022-03-03

5.  It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer.

Authors:  Ingrid Garajová; Andrea Cavazzoni; Michela Verze; Roberta Minari; Giuseppe Pedrazzi; Rita Balsano; Fabio Gelsomino; Raffaele Dalla Valle; Graziana Digiacomo; Elisa Giovannetti; Francesco Leonardi
Journal:  Life (Basel)       Date:  2022-06-26

6.  Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice.

Authors:  Kathrin Hedegger; Hana Algül; Marina Lesina; Andreas Blutke; Roland M Schmid; Marlon R Schneider; Maik Dahlhoff
Journal:  Mol Oncol       Date:  2020-05-18       Impact factor: 6.603

  6 in total

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