Robert L Newton1, William D Johnson2, Chelsea Hendrick3, Melissa Harris4, Emanuel Andrews5, Neil Johannsen6, Ruben Q Rodarte7, Daniel S Hsia8, Timothy S Church9. 1. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Robert.Newton@pbrc.edu. 2. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: William.Johnson@pbrc.edu. 3. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Chelsea.Hendrick@pbrc.edu. 4. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Melissa.Harris@pbrc.edu. 5. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Emanuel.Andrews@pbrc.edu. 6. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA; Louisiana State University, 112 Huey P. Long Field House, Baton Rouge, LA, 70803, USA. Electronic address: njohan1@lsu.edu. 7. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA; ACAP Health, 12712 Park Central Dr., Suite 100, Dallas, TX 75251, USA. Electronic address: RRodarte@acaphealth.com. 8. Louisiana State University, 112 Huey P. Long Field House, Baton Rouge, LA, 70803, USA. Electronic address: Daniel.Hsia@pbrc.edu. 9. Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA; ACAP Health, 12712 Park Central Dr., Suite 100, Dallas, TX 75251, USA. Electronic address: Timothy.Church@pbrc.edu.
Abstract
BACKGROUND: Lack of regular physical activity at prescribed intensity levels is a modifiable risk factor for insulin resistance and the development of diabetes. African American men are at increased risk for developing diabetes and most African American men are not meeting the current recommended levels of physical activity. The primary objective of the Aerobic Plus Resistance Training and Insulin Resistance in African American Men (ARTIIS) study is to determine the effectiveness of an exercise training intervention aimed at reducing diabetes risk factors in African American men at risk for developing diabetes. METHODS:Insufficiently active 35-70 year old African American men with a family history of diabetes were eligible for the study. The 5-month randomized controlled trial assigns 116 men to anexercise trainingor healthy living control arm. The exercise training arm combines aerobic and resistance training according to the current national physical activity recommendations and is conducted in community (YMCA) facilities. The healthy living arm receives information promoting healthy lifestyle changes. OUTCOMES: Insulin response to an oral glucose load is the primary outcome measure, and changes in physiological parameters, cardiorespiratory fitness, strength, body composition, and psychological well-being comprise the secondary outcomes. CONCLUSIONS: The ARTIIS study is one of the first adequately powered, rigorously designed studies to investigate the effects of an aerobic plus resistance exercise training program and to assess adherence to exercise training in community facilities, in African American men.
RCT Entities:
BACKGROUND: Lack of regular physical activity at prescribed intensity levels is a modifiable risk factor for insulin resistance and the development of diabetes. African American men are at increased risk for developing diabetes and most African American men are not meeting the current recommended levels of physical activity. The primary objective of the Aerobic Plus Resistance Training and Insulin Resistance in African American Men (ARTIIS) study is to determine the effectiveness of an exercise training intervention aimed at reducing diabetes risk factors in African American men at risk for developing diabetes. METHODS:Insufficiently active 35-70 year old African American men with a family history of diabetes were eligible for the study. The 5-month randomized controlled trial assigns 116 men to an exercise training or healthy living control arm. The exercise training arm combines aerobic and resistance training according to the current national physical activity recommendations and is conducted in community (YMCA) facilities. The healthy living arm receives information promoting healthy lifestyle changes. OUTCOMES: Insulin response to an oral glucose load is the primary outcome measure, and changes in physiological parameters, cardiorespiratory fitness, strength, body composition, and psychological well-being comprise the secondary outcomes. CONCLUSIONS: The ARTIIS study is one of the first adequately powered, rigorously designed studies to investigate the effects of an aerobic plus resistance exercise training program and to assess adherence to exercise training in community facilities, in African American men.
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