Literature DB >> 25977578

Targets of opportunity for precision medicine.

Yogen Saunthararajah1.   

Abstract

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Year:  2015        PMID： 25977578      PMCID： PMC4432001          DOI： 10.1182/blood-2015-04-638270

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  8 in total

1.  Polycomb segment myeloid malignancies.

Authors:  Yogen Saunthararajah; Jaroslaw Maciejewski
Journal:  Blood       Date:  2012-02-02       Impact factor: 22.113

2.  IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.

Authors:  Carolina Schinke; Orsolya Giricz; Weijuan Li; Aditi Shastri; Shanisha Gordon; Laura Barreyro; Laura Barreryo; Tushar Bhagat; Sanchari Bhattacharyya; Nandini Ramachandra; Matthias Bartenstein; Andrea Pellagatti; Jacqueline Boultwood; Amittha Wickrema; Yiting Yu; Britta Will; Sheng Wei; Ulrich Steidl; Amit Verma
Journal:  Blood       Date:  2015-03-25       Impact factor: 22.113

3.  Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

Authors:  Max Jan; Thomas M Snyder; M Ryan Corces-Zimmerman; Paresh Vyas; Irving L Weissman; Stephen R Quake; Ravindra Majeti
Journal:  Sci Transl Med       Date:  2012-08-29       Impact factor: 17.956

4.  Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.

Authors:  Nina Cabezas-Wallscheid; Daniel Klimmeck; Jenny Hansson; Daniel B Lipka; Alejandro Reyes; Qi Wang; Dieter Weichenhan; Amelie Lier; Lisa von Paleske; Simon Renders; Peer Wünsche; Petra Zeisberger; David Brocks; Lei Gu; Carl Herrmann; Simon Haas; Marieke A G Essers; Benedikt Brors; Roland Eils; Wolfgang Huber; Michael D Milsom; Christoph Plass; Jeroen Krijgsveld; Andreas Trumpp
Journal:  Cell Stem Cell       Date:  2014-08-21       Impact factor: 24.633

5.  Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.

Authors:  Yogen Saunthararajah; Mikkael Sekeres; Anjali Advani; Reda Mahfouz; Lisa Durkin; Tomas Radivoyevitch; Ricki Englehaupt; Joy Juersivich; Kathleen Cooper; Holleh Husseinzadeh; Bartlomiej Przychodzen; Matthew Rump; Sean Hobson; Marc Earl; Ronald Sobecks; Robert Dean; Frederic Reu; Ramon Tiu; Betty Hamilton; Edward Copelan; Alan Lichtin; Eric Hsi; Matt Kalaycio; Jaroslaw Maciejewski
Journal:  J Clin Invest       Date:  2015-01-26       Impact factor: 14.808

6.  Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission.

Authors:  M Ryan Corces-Zimmerman; Wan-Jen Hong; Irving L Weissman; Bruno C Medeiros; Ravindra Majeti
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-03       Impact factor: 11.205

7.  Runx1 deficiency permits granulocyte lineage commitment but impairs subsequent maturation.

Authors:  K P Ng; Z Hu; Q Ebrahem; S Negrotto; J Lausen; Y Saunthararajah
Journal:  Oncogenesis       Date:  2013-11-04       Impact factor: 7.485

8.  Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.

Authors:  Liran I Shlush; Sasan Zandi; Amanda Mitchell; Weihsu Claire Chen; Joseph M Brandwein; Vikas Gupta; James A Kennedy; Aaron D Schimmer; Andre C Schuh; Karen W Yee; Jessica L McLeod; Monica Doedens; Jessie J F Medeiros; Rene Marke; Hyeoung Joon Kim; Kwon Lee; John D McPherson; Thomas J Hudson; Andrew M K Brown; Fouad Yousif; Quang M Trinh; Lincoln D Stein; Mark D Minden; Jean C Y Wang; John E Dick
Journal:  Nature       Date:  2014-02-12       Impact factor: 69.504
  8 in total

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