Literature DB >> 2597691

The development expression of alpha-, mu- and pi-class glutathione S-transferases in human liver.

R C Strange1, A F Howie, R Hume, B Matharoo, J Bell, C Hiley, P Jones, G J Beckett.   

Abstract

The developmental expression of the alpha, mu and pi class glutathione S-transferases has been defined in human liver using radioimmunoassay and immunohistochemistry. Expression of alpha and mu class isoenzymes increased significantly at birth, while that of the pi isoenzyme declined during the first trimester. Mu-class isoenzymes (GST1 1, GST1 2, GST1 2-1) were expressed in hepatocytes but not in other liver cell types.

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Year:  1989        PMID: 2597691     DOI: 10.1016/0304-4165(89)90162-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  19 in total

1.  Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes.

Authors:  Stephan C Jahn; Lauren A Gay; Claire J Weaver; Rolf Renne; Taimour Y Langaee; Peter W Stacpoole; Margaret O James
Journal:  Drug Metab Dispos       Date:  2020-05-01       Impact factor: 3.922

2.  Prediction of Clearance, Volume of distribution, and Half-life of Drugs in Extremely Low to Low Birth Weight Neonates: An Allometric Approach.

Authors:  Iftekhar Mahmood
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2017-08       Impact factor: 2.441

3.  Developmental pharmacology and toxicology: biotransformation of drugs and other xenobiotics during postnatal development.

Authors:  Wolfgang Klinger
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2005 Jan-Jun       Impact factor: 2.441

4.  Glutathione S-transferase expression in primary biliary cirrhosis supports concept of "ductular metaplasia" of hepatocytes.

Authors:  C G Hiley; R C Strange; M H Davies; E Elias; S G Hubscher
Journal:  J Clin Pathol       Date:  1993-04       Impact factor: 3.411

Review 5.  The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer.

Authors:  Kenneth D Tew; Yefim Manevich; Christina Grek; Ying Xiong; Joachim Uys; Danyelle M Townsend
Journal:  Free Radic Biol Med       Date:  2011-04-22       Impact factor: 7.376

6.  Bisphenol A-associated alterations in the expression and epigenetic regulation of genes encoding xenobiotic metabolizing enzymes in human fetal liver.

Authors:  Muna S Nahar; Jung H Kim; Maureen A Sartor; Dana C Dolinoy
Journal:  Environ Mol Mutagen       Date:  2013-11-09       Impact factor: 3.216

Review 7.  Ontogeny of hepatic and renal systemic clearance pathways in infants: part I.

Authors:  Jane Alcorn; Patrick J McNamara
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

Review 8.  Fulminant hepatic failure associated with status epilepticus in children: three cases and a review of potential mechanisms.

Authors:  M K Decell; J B Gordon; K Silver; K Meagher-Villemure
Journal:  Intensive Care Med       Date:  1994-05       Impact factor: 17.440

9.  Prediction of glucuronidated drug clearance in pediatrics (≤5 years): An allometric approach.

Authors:  Iftekhar Mahmood
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2014-02-12       Impact factor: 2.441

10.  A framework and case studies for evaluation of enzyme ontogeny in children's health risk evaluation.

Authors:  Gary Ginsberg; Suryanarayana V Vulimiri; Yu-Sheng Lin; Jayaram Kancherla; Brenda Foos; Babasaheb Sonawane
Journal:  J Toxicol Environ Health A       Date:  2017-09-11
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